SCOPUS 정보 검색 플랫폼

Bailliere's Best Practice and Research in Clinical Anaesthesiology

Volumn 14, Issue 2, 2000, Pages 237-246

A historical perspective: Development of clonidine

a BOEHRINGER INGELHEIM PHARMA GMBH AND CO KG (Germany)

Author keywords

Central adrenoceptors; Chemical discovery; Chemical structure; Clonidine; Discovery of blood pressure lowering activity; Structure activity relationships

Indexed keywords

ALPHA 2A ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR; AMIDINE; ANILINE DERIVATIVE; CLONIDINE; ETHYLENEDIAMINE; IMIDAZOLIDINE DERIVATIVE; NAPHAZOLINE; NORADRENALIN; PHENTOLAMINE; TOLAZOLINE;

ALPHA ADRENERGIC RECEPTOR BLOCKING; BRADYCARDIA; DRUG ABSORPTION; DRUG CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG WITHDRAWAL; EXPERIMENTAL MODEL; GLAUCOMA; HUMAN; HYPERTENSION; HYPOTENSION; MIGRAINE; NONHUMAN; NOSE CONGESTION; PRIORITY JOURNAL; REVIEW; STRUCTURE ACTIVITY RELATION; TREATMENT INDICATION; VASOCONSTRICTION; XEROSTOMIA;

EID: 0033742770 PISSN: 15216896 EISSN: None Source Type: Journal
DOI: 10.1053/bean.2000.0079 Document Type: Article

Times cited : (43)

References (38)

1
- 85031613157
- Kreislaufmittel-Sympathomimetica und Sympatholytica (Adrenolytica)
- In Ehrhart G and Ruschig H (eds); Weinheim: Verlag Chemie; 2nd edn.
- (1972) Arzneimittel , vol.2 , pp. 131
- Soldan, F.¹ Druckrey, E.² Hartfelder, G.³

2
- 0007310344
- Antihypertensive agents
- In Burger A (ed.); New York: Wiley-Interscience; 3rd edn.
- (1970) Medicinal Chemistry , pp. 1050
- Comer, W.T.¹ Gomoll, A.W.²

3
- 0007188240
- (1961) Bulletin Societe Chim Francaise , pp. 2114
- Najer, H.¹ Giudicelli, R.² Sette, J.³

4
- 0007177557
- Synthesis of 1,3-Diazacycio-alkenes-2
- New York (inventor: BM Bloom). U.S.; Patent 2,899,426 (August 11, 1959)
- (1960) Chemical Abstracts , vol.54 , pp. 588

5
- 85031604093
- Ingelheim/Rheim (inventors: H Stahle and K Zeile). German Patent 1,670,162 (29 June 1978/31 October 1966)
- Verfahren zur Herstellung Von 2-substituierten Phenylamino-1,3-diazacycloalkenen-(2) und Deren Saureadditionssalze
- Boehringer Sohn, C.H.¹

6
- 85031608468
- Ingelheim/Rhein (inventors: K Zeile, H Stahle and KH Hauptman). German Patent 1,303,141 (9 October 1961/11 January 1973)
- Disubstituierte 2-Phenylamino-1,3-diazacyclopentene-(2)
- Boehringer Sohn, C.H.¹

7
- 0007177558
- Heidelberg: Alfred Huthig Verlag
- (1956) Die Insektizide. Chemie, Wirkungsweise und Toxizitat
- Perkow, W.¹

8
- 0007324474
- Muller P (Ed.); Basel: Birkhauser Verlag
- (1955) DDT. Insecticides , vol.1

9
- 0007250683
- Personal communication
- (1962)
- Hoefke, W.¹

10
- 0007303153
- (1929) Presse Medicale , pp. 1637
- Buiet, L.¹ Araudine, L.²

11
- 0007188241
- Personal communication
- (1962)
- Wolf, M.¹

12
- 0013938834
- (1966) ArzneimiHelforschung (Drug Research) , vol.16 , pp. 1055
- Graubner, W.¹ Wolf, M.²

13
- 0007310345
- Imidazoline - New facets of a Cinderella molecule
- In McMahon FG (ed.); NY, Mount Kisco: Futura Publishing
- (1978) Future Trends in Therapeutics. Principles and Techniques of Human Research and Therapeutics , vol.15 , pp. 179
- Wolf, M.¹ Morr, H.²

14
- 0017923173
- (1978) Revu Physiol Biochem. Pharmacol. , vol.81 , pp. 39
- Kobinger, W.¹

15
- 0002218064
- Clonidine
- In Goldberg ME (ed.); Washington, DC: American Pharmaceutical Association
- (1977) Pharmacological and Biochemical Properties and Drug Substances , vol.1 , pp. 67
- Walland, A.¹

16
- 0007314395
- (1973) Chim. Ther. , pp. 545
- Rouot, B.¹ Leclerc, G.² Wermuth, C.G.³

17
- 84982072117
- (1974) Chem. Ber. , vol.107 , pp. 2644
- Pook, K.-H.¹ Stahle, H.² Daniel, H.³

18
- 85031599093
- Unpublished data
- (1971)
- Stahle, H.¹ Heel, W.² Becker, J.³

19
- 0015373928
- (1972) Journal of Medical Chemistry , vol.15 , pp. 727
- Jen, T.¹ Dienel, B.² Bowman, H.³

20
- 0017056293
- (1976) Acta Chimica Scandinavica , vol.30 B , pp. 843
- Byre, G.¹ Mostad, A.² Romming, C.³

21
- 0015251123
- (1972) Journal of Medical Chemistry , vol.15 , pp. 17
- Puilman, B.¹ Coubeils, J.L.² Courriere, P.³ Gervois, I.P.⁴

22
- 0015339597
- (1972) Journal of Medical Chemistry , vol.15 , pp. 453
- Coubeik, J.L.¹ Courriere, P.² Pullman, B.³

23
- 0007247103
- (1973) Chim. Ther. , pp. 115
- Wermuth, C.G.¹ Schwartz, L.² Leclerc, G.³

24
- 0016836431
- (1975) Life Sciences , vol.17 , pp. 377
- Struyker Boudier, H.¹ De Boer, J.² Smeets, G.³

25
- 0016745150
- (1975) Arzneim. Forsch. (Drug Research) , vol.25 , pp. 786
- Hoefke, W.¹ Kobinger, W.² Walland, A.³

26
- 0017169696
- (1976) Journal of Medical Chemistry , vol.19 , pp. 1049
- Rouot, B.¹ Leclerc, G.² Wermuth, C.G.³

27
- 0017712973
- (1977) Journal of Medical Chemistry , vol.20 , pp. 1636
- Timmermans, P.B.M.W.M.¹ Van Zwieten, P.A.²

28
- 85031605077
- (submitted for publication)
- Progress in Pharmacology
- Stahle, H.¹ Hoefke, W.²

29
- 0142170703
- Structure-activity relationships in clonidine-like imidazolidines and related compounds
- In Grobecker H, Kahl GF, Klaus W and van Zwieten PA (eds); Stuttgart: Gustav Fischer Verlag
- (1980) Progress in Pharmacology
- Timmermans, P.B.M.W.M.¹ Hoefke, W.² Stahle, H.³ Van Zwieten, P.A.⁴

30
- 0001454089
- Quantitative structure-activity relationships in drug design
- In Ariens EJ (ed.); New York: Academic Press
- (1971) Drug Design , vol.1 , pp. 271
- Hansch, C.¹

31
- 0002109773
- Quantitative approaches to pharmacological structure-activity relationships
- In Cavallito CJ (ed.); London: Pergamon Press
- (1973) Structure-Activity Relationships , vol.1 , pp. 75
- Hansch, C.¹

32
- 0007243812
- The relationship between chemical structure and drug absorption, distribution and excretion
- In Maas J (ed.); Amsterdam: Elsevier
- (1974) Medicinal Chemistry IV. Proceedings of the 4th International Symposium on Medicinal Chemistry, Noordwijkerhout, The Netherlands, September 9-13, 1974 , pp. 319
- Lien, E.J.¹

33
- 0017642360
- (1977) Archives of Ophthalmology , vol.95 , pp. 1368
- Harrison, R.¹ Kaufmann, C.S.²

34
- 0014885453
- (1972) Research and Clinical Studies in Headache , vol.3 , pp. 315
- Wilkinson, M.¹

35
- 0018305396
- (1979) Lancet , vol.2 , pp. 278
- Gil-Ad, I.¹ Topper, E.² Laron, Z.³

36
- 84921109872
- Effect of clonidine on HGH release in psychiatric patients and controls
- Hawaii
- (1977) 6th World Congress of Psychiatry
- Matussek, N.¹ Ackenheil, M.² Hippius, H.³

37
- 0018097616
- (1978) Lancet , vol.1 , pp. 929
- Gold, M.S.¹ Redmond, D.G.² Kleber, H.D.³

38
- 0018412220
- (1979) American Journal of Psychiatry , vol.136 , pp. 100
- Gold, M.S.¹ Redmond D.E., Jr.² Kleber, H.D.³

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.