An improved procedure for the preparation of the endothelin-B-receptor ligand sarafotoxin 6c

Journal of Cardiovascular Pharmacology

Volumn 36, Issue 5 SUPPL. 1, 2000, Pages

  Langlois, C ^a   Tessier, S ^a   Brkovic, A ^a   Fournier, A ^a  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

Author keywords

ET(B); Fmoc chemistry; Peptide synthesis; Sarafotoxin

Indexed keywords

9 FLUORENYLMETHOXYCARBONYL AMINO ACID; AMINO ACID DERIVATIVE; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR AGONIST; FERRIC ION; FERROUS ION; SARAFOTOXIN S6C; SILVER DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; BIOASSAY; CONTROLLED STUDY; CYCLIZATION; DISULFIDE BOND; DRUG PURIFICATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; LIGAND BINDING; LUNG PARENCHYMA; MASS SPECTROMETRY; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SMOOTH MUSCLE CONTRACTION;

EID: 0033735046     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200036001-00091     Document Type: Article

References (7)

1. Sarafotoxin, a novel vasoconsrictor peptide: Phosphoinositide hydrolysis in rat heart and brain
2. SRTX-d, a new native peptide of the endothelin/sarafotoxin family
3. Similarities in mode and sites of action of sarafotoxins and endothelins
4. An improved method for anchoring of 9-fluorenyl-methoxycarbonyl-amino acids to 4-alkoxybenzyl alcohol resin
5. Solid phase peptide synthesis utilising 9-fluorenylmethoxycarbonyl amino acids
6. Color test for studies of Fmoc-Cys(Trt)-OH during stepwise Fmoc-solid phase peptide synthesis
7. Biological and molecular analyses of structurally reduced analogues of endothelin-1