Refractory pretibial myxoedema with response to intralesional insulin-like growth factor 1 antagonist (octreotide): Downregulation of hyaluronic acid production by the lesional fibroblasts

British Journal of Dermatology

Volumn 143, Issue 5, 2000, Pages 1083-1086

  Shinohara, M ^a   Hamasaki, Y ^a   Katayama, I ^a  

^a NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Hyaluronic acid; Insulin like growth factor 1 antagonist; Pretibial myxoedema

Indexed keywords

HYALURONIC ACID; OCTREOTIDE; SOMATOMEDIN C; SOMATOMEDIN C RECEPTOR;

AGED; ARTICLE; CASE REPORT; CLINICAL FEATURE; DIAGNOSTIC PROCEDURE; DISEASE COURSE; GRAVES DISEASE; HISTOPATHOLOGY; HUMAN; MALE; MYXEDEMA; PRIORITY JOURNAL; SKIN BIOPSY; SKIN FIBROBLAST; TIBIA; TREATMENT OUTCOME;

DOWN-REGULATION; FIBROBLASTS; HORMONES; HUMANS; HYALURONIC ACID; INSULIN-LIKE GROWTH FACTOR I; LEG DERMATOSES; MALE; MIDDLE AGED; MYXEDEMA; OCTREOTIDE;

EID: 0033730232     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2000.03850.x     Document Type: Article

References (10)

1. Pretibial myxoedema (Report of 17 cases and review of the literature)
2. Dermopathy of Graves' disease (pretibial myxoedema)
3. Octreotide and Graves' ophthalmopathy and pretibial myxoedema
4. A rapid and micro method for separation of actinic glycosaminoglycans by two-dimensional electrophoresis
5. Assay of serum hyaluronic acid in clinical application
6. Pathogenesis and treatment of pretibial myxoedema
7. Biological activity of autoantibodies associated with Graves' dermopathy
8. Analysis of fibroblast-stimulating activity in IgG from patients with Graves' dermopathy
9. Extrathyroidal complications of Graves' disease
10. Skin fibroblast activity in pretibial myxoedema and the effect of octreotide (Sandostatin) in vitro