Correlation between 5-HT content and uptake site density following (S)-MDMA and dexfenfluramine-induced depletion, and with neuroprotection by the glycine site-specific NMDA antagonist ACEA 1021

Annals of the New York Academy of Sciences

Volumn 914, Issue , 2000, Pages 208-214

  Russell, B R ^a   Laverty, R ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; 6,7 DICHLORO 5 NITRO 2,3 QUINOXALINEDIONE; DEXFENFLURAMINE; GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; PAROXETINE; SEROTONIN; TRITIUM;

ANIMAL EXPERIMENT; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DRUG UPTAKE; ISOTOPE LABELING; MALE; NEUROTOXICITY; NONHUMAN; RAT; SEROTONIN RELEASE; SEROTONINERGIC SYSTEM; TISSUE DISTRIBUTION;

ANIMALIA; TRITIUM;

EID: 0033724760     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2000.tb05197.x     Document Type: Article

References (26)

1. Action of fenfluramine on monoamine stores of rat tissues
2. Acute administration of methylenedioxymethamphetamine: Comparison with the neurochemical effects of its N-desmethyl and N-ethyl analogs
3. Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine
4. 3H]paroxetine-labeled serotonin uptake sites
5. Long-term effects of fenfluramine on central serotonergic mechanisms
6. Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain
7. Neurotoxicity profiles of substituted amphetamines in the C57BL/6J mouse
8. Dexfenfluramine and serotonin neurotoxicity: Further preclinical evidence that clinical caution is indicated
9. Age-dependent sensitivity of rats to the long-term effects of the serotonergic neurotoxicant (±)-3,4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response
10. The effect of MDMA (3,4-methylenedioxymethamphetamine) on the 5-HT synthesis rate in the rat brain: An autoradiographic study
11. Protection by MK 801 and other drugs of methylenedioxy-methamphetamine (MDMA) neurotoxicity in rats and mice
12. Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3,4-methylenedioxymethamphetamine): Assessment using quantitative autoradiography
13. 3H]imipramine localization and relationship to serotonin transporter
14. Actions of drugs that deplete serotonin
15. Serotonin and lysergic acid diethylamide binding in rat brain membranes: Relationship to postsynaptic serotonin receptors
16. Paroxetine as an in vivo indicator of 3,4-methylenedioxymethamphetamine neurotoxicity: A presynaptic serotonergic positron emission tomography ligand?
17. Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats
18. Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine
19. Role of hypothermia in the mechanism of protection against serotonergic toxicity. I. Experiments using 3,4-methylenedioxymethamphetamine, dizocilpine, CGS 19755 and NBQX
20. Differential effects of agents acting at various sites of the NMDA receptor complex in a place preference conditioning model
21. R-(+)-HA-966, an antagonist for the glycine/NMDA receptor, prevents locomotor sensitization to repeated cocaine exposures
22. The NMDA receptor antagonist MK-801 does not protect against serotonin depletions caused by high doses of DL-fenfluramine
23. Protein measurement with the folin phenol reagent
24. MK-801, but not drugs acting at strychnine-insensitive glycine receptors, attenuate methamphetamine nigrostriatal toxicity