Antidiuretic effects of a nonpeptide vasopressin V2-receptor agonist, OPC-51803, administered orally to rats

Journal of Pharmacology and Experimental Therapeutics

Volumn 295, Issue 3, 2000, Pages 1005-1011

  Nakamura, Shigeki ^a   Hirano, Takahiro ^a   Tsujimae, Kenji ^a   Aoyama, Masashi ^a   Kondo, Kazumi ^a   Yamamura, Yoshitaka ^a   Mori, Toyoki ^a   Tominaga, Michiaki ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2 [1 (2 CHLORO 4 (1 PYRROLIDINYL)BENZOYL) 2,3,4,5 TETRAHYDRO 1H BENZAZEPIN 5 YL] N ISOPROPYLACETAMIDE; OPC 51803; UNCLASSIFIED DRUG; VASOPRESSIN RECEPTOR ANTAGONIST; VASOPRESSIN V2 RECEPTOR;

ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES INSIPIDUS; DIURESIS; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG RECEPTOR BINDING; FEMALE; HORMONE BLOOD LEVEL; KIDNEY; LIVER; MALE; NOCTURIA; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR AFFINITY; URINE INCONTINENCE; URINE OSMOLALITY;

ADMINISTRATION, ORAL; ANIMALS; ARGININE VASOPRESSIN; BENZAZEPINES; BLOOD PRESSURE; CREATININE; DIABETES INSIPIDUS; DIURESIS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; KIDNEY; LIVER; MALE; PYRROLIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, VASOPRESSIN;

EID: 0033712423     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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