Systemic administration of a novel octapeptide, amylin-(1-8), increases bone volume in male mice

American Journal of Physiology - Endocrinology and Metabolism

Volumn 279, Issue 4 42-4, 2000, Pages

  Cornish, Jillian ^a   Callon, Karen E ^a   Gasser, Juerg A ^c   Bava, Usha ^a   Gardiner, Edith M ^d   Coy, David H ^a,e   Cooper, Garth J S ^a,b   Reid, Ian R ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c NOVARTIS PHARMA AG   (Switzerland)

^d GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^e TULANE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Amylin; Bone growth; Osteoblast; Osteoporosis; Peptide hormones

Indexed keywords

AMYLIN; AMYLIN[1-8]; OCTAPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE STRENGTH; CONTROLLED STUDY; CORTICAL BONE; DOSE RESPONSE; MALE; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOPOROSIS; PRIORITY JOURNAL; TRABECULAR BONE; TREATMENT OUTCOME;

EID: 0033711862     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.2000.279.4.e730     Document Type: Article

References (13)

1. Targeted expression of calcitonin gene-related peptide to osteoblasts increases bone density in mice
2. Calcitonin gene-related peptide, amylin, or parathyroid hormone stimulate (in vitro) biomineralization
3. Amylin compared with calcitonin gene-related peptide-structure, biology, and relevance to metabolic disease
4. Amylin stimulates osteoblast proliferation and increases mineralized bone volume in adult mice
5. Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo
6. Systemic administration of amylin increases bone mass, linear growth, and adiposity in adult male mice
7. Comparison of the effects of calcitonin gene-related peptide and amylin on osteoblasts
8. Dissociation of the effects of amylin on osteoblast proliferation and bone resorption
9. Densitometry-based equations for estimating body composition in Fischer rats
10. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and osteoporosis
11. Calcitonin gene related peptide enhances bone colony development in vitro
12. Effects of calcitonin gene-related peptide on bone turnover in ovariectomized rats
13. Effects of amylin on human osteoblast-like cells