(8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1, 3, 8-triaza-spiro[4.5]-dec-3-yl)-ace tic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist

British Journal of Pharmacology

Volumn 131, Issue 5, 2000, Pages 903-908

  Thomsen, Christian ^a,b   Hohlweg, Rolf ^a  

^a NOVO NORDISK A S   (Denmark)

^b H LUNDBECK A S   (Denmark)

Author keywords

Nociceptin receptor; Opioid receptor spiroxatrine; ORL1; Orphanin FQ

Indexed keywords

(8 NAPHTHALEN 1 YL METHYL 4 OXO 1 PHENYL 1,3,8 TRIAZASPIRO[4.5]DEC 3 YL)ACETIC ACID METHYL ESTER; DOPAMINE RECEPTOR; NOCICEPTIN; NOCICEPTIN RECEPTOR; OPIATE RECEPTOR; SPIROXATRINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; BLOOD BRAIN BARRIER; CHEMICAL MODIFICATION; NONHUMAN; PRIORITY JOURNAL; RECEPTOR AFFINITY;

ACETIC ACIDS; ANIMALS; CRICETINAE; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; RATS; RECEPTORS, OPIOID; SPIRO COMPOUNDS;

EID: 0033709561     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703661     Document Type: Article

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