Micronucleus formation induced by the combination of low doses of X-rays and antineoplastic drugs in bone marrow of male mice

Teratogenesis Carcinogenesis and Mutagenesis

Volumn 20, Issue 6, 2000, Pages 321-327

  Dobrzyska, Malgorzata M ^a  

^a NATIONAL INSTITUTE OF HYGIENE   (Poland)

Author keywords

Combined treatment; Cyclophosphamide; Mitomycin C; Nonmutagenic doses; Vinblastine; X rays

Indexed keywords

ANTINEOPLASTIC AGENT; CYCLOPHOSPHAMIDE; MITOMYCIN C; VINBLASTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CANCER CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; ENVIRONMENTAL EXPOSURE; MALE; MICRONUCLEUS; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RADIATION DOSE; RADIATION EXPOSURE; X RAY;

ANIMALS; ANTINEOPLASTIC AGENTS; BONE MARROW CELLS; CYCLOPHOSPHAMIDE; ERYTHROCYTES; MALE; MICE; MICRONUCLEUS TESTS; MITOMYCIN; VINBLASTINE;

ANIMALIA;

EID: 0033695333     PISSN: 02703211     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-6866(2000)20:6<321::AID-TCM1>3.0.CO;2-C     Document Type: Article

References (38)

1. Dose response at low doses of X-irradiation and MMS on the induction of micronuclei in mouse erythroblasts
2. Factors affecting the induction of micronuclei of low doses of X-rays, MMC and diethylnitrosoamina in mouse erythroblasts
3. Recovery of polychromatic erythrocytes and micronuclei following cellulose column seperation of mouse bone-marrow samples
4. Effects of copperglycinate on the radiation induced micronuclei formation in mice bone marrow
5. Kinetochore identification in micronuclei in mouse bone marrow erythrocytes: An assay for the detection of aneuploidy-inducting agents
6. Kinetochore-staining of spermatid micronuclei: Studies of mice treated with X-radiation or acrylamide
7. Interaction of chemotherapeutic agents in radiation
8. The cellular basis of cancer chemotherapy
9. Micronucleus test and bone-marrow chromosome analysis: A comparison of two methods in vivo for evaluating chemically induced chromosomal alterations
10. High sensitivity in micronucleus induction of mouse strain (MS)
11. Rates of micronuclei induction in different mouse strains
12. Relationship between experimental results in mammalian and man. I. Cytogenetic analysis of bone marrow injury induced by a single dose of cyclophosphamide
13. Cytogenetic investigations of mammals: Comparison of the genetic activity of cytostatics in mammals
14. Effects of various cyclophosphamide concentrations in vivo on sister chromatid exchanges (SCE) and chromosome aberrations in Chinese hamster bone marrow cells
15. Species differences in mutagenicity testing. II. Sister-chromatid exchange and micronucleus induction in rats, mice and Chinese hamster treated with cyclophosphamide
16. Comparison of single and multiple treatment regiments in the mouse bone marrow micronucleus assay for hydroquinone (HQ) and cyclophosphamide (CP)
17. Cyclophosphamide: Review of its mutagenicity for an assessment of potential germ cell risks
18. Microtubules
19. A search for in vivo factors in regulation of microtubule assemby
20. The micronucleus test
21. Induction of micronuclei in mouse bone marrow after combined X-rays-cyclophosphamide and X-rays-mitomycin C treatments
22. The time course of micronucleated polychromatic erythrocytes in mouse bone marrow and peripheral blood
23. The micronucleus test in rat erythrocytes from bone marrow, spleen and peripheral blood: The response to low doses of ionizing radiation, cyclophosphamide and vincristine determined by flow cytometry
24. Micronucleus test with cyclophosphamide administered by intraperitoneal injection and oral gavage
25. Towards an improved micronucleus test. Studies on 3 model agents, mitomycin C, cyclophosphamide and diethylbenzanthracene
26. A comparison of intraperitonal injection and oral gavage in the micronucleus test with mitomycin C in mice
27. Difference between intraperitoneal and oral gavage application in micronucleus test
28. Micronucleus morphology as a means to distinquish aneugens and clastogens in the mouse bone marrow micronucleus assay
29. Vinblastine treatment induces dose dependent increases in the frequency of micronuclei in mice bone marrow
30. Biochemical pharmacology of chemiotherapeutic drugs used as radiation enhancers
31. Chromosome and SCE analysis in peripheral lymphocytes of persons occupationally exposed to cytostatic drugs handled with and without use of safety covers
32. Comparison of methods for the biomonitoring of nurses handling antitumor drugs
33. Biomonitoring of nurses handling antineoplastic drugs
34. DNA damage in nurses handling antineoplastic agents
35. Cytogenetic consequences after occupational exposure to antineoplasic drugs
36. Assessment of DNA damage in nurses handling antineoplastic drugs by the alkaline COMET assay