Effect of Y-24180, a receptor antagonist to platelet-activating factor (PAF), on allergic cutaneous reactions in actively sensitized mice

Inflammation Research

Volumn 49, Issue 11, 2000, Pages 584-590

  Yamaguchi, S ^a   Tomomatsu, N ^a   Komatsu, H ^a  

^a Welfide Corporation   (Japan)

Author keywords

Cutaneous reaction; Eosinophil; IgE; Mouse; PAF; Y 24180

Indexed keywords

HYDROCORTISONE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; ISRAPAFANT; KETOTIFEN FUMARATE; OVALBUMIN; SUPLATAST TOSYLATE; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY TITER; ARTICLE; ATOPIC DERMATITIS; DRUG EFFICACY; DRUG POTENTIATION; IMMEDIATE TYPE HYPERSENSITIVITY; MALE; MOUSE; NONHUMAN; SENSITIZATION; SKIN ALLERGY;

ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ALLERGENS; ANIMALS; ANTI-ALLERGIC AGENTS; ANTI-INFLAMMATORY AGENTS; ARYLSULFONATES; AZEPINES; DERMATITIS, ALLERGIC CONTACT; EAR; EOSINOPHILS; HISTAMINE H1 ANTAGONISTS; HYDROCORTISONE; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; KETOTIFEN; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; OVALBUMIN; PLATELET MEMBRANE GLYCOPROTEINS; RECEPTORS, CELL SURFACE; RECEPTORS, G-PROTEIN-COUPLED; SULFONIUM COMPOUNDS; TIME FACTORS; TRIAZOLES;

EID: 0033695054     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110050635     Document Type: Article

References (29)

1. Late cutaneous allergic responses in isolated IgE-dependent reactions
2. The late phase of the immunoglobulin E mediated reaction: A link between anaphylaxis and common allergic disease?
3. The late phase of the immediate wheal and flare skin reaction: Its dependence upon IgE antibodies
4. Cutaneous late-phase response to allergen. Mediator release and inflammatory cell infiltration
5. Expression of endothelial-leukocyte adhesion molecule-1 in elicited late phase allergic reaction
6. Assessment of eosinophil and neutrophil participation in atopic dermatitis: Comparison with the IgE-mediated late-phase reaction
7. Induction of eczematous skin reaction in experimentally induced hyperplastic skin of Balb/C mice by monoclonal anti-DNP IgE antibody: Possible implications for skin lesion formation in atopic dermatitis
8. An immunopharmacological study of the biphasic allergic skin reaction in mice
9. Pharmacological actions of Y-24180, a new specific antagonist of platelet activating factor (PAF): II. Interactions with PAF and benzodiazepine receptors
10. Pharmacological actions of Y-24180: I. A potent and specific antagonist of platelet-activating factor
11. Effect of Y-24180, an antagonist at platelet-activating factor (PAF) receptors, on IgE-mediated cutaneous reactions in mice
12. Inhibition of immunological histamine release from guinea pig lungs and other organs by mepyramine, ketotifen, and picumast in vivo
13. Down-regulation of Th2 cell-mediated murine peritoneal eosinophilia by antiallergic agents
14. Suppression of the arthus reaction by Y-24180, a potent and specific antagonist of platelet-activating factor
15. Platelet-activating factor as a mediator of allergic disease
16. Endogenous platelet-activating factor is critically involved in effector functions of eosinophils stimulated with IL-5 or IgG
17. Anti-IL-5 monoclonal antibody inhibits allergic late phase bronchial eosinophilia in guinea pigs: A therapeutic approach
18. Effect of anti-IL-5 monoclonal antibody on allergic bronchial eosinophilia and airway hyperresponsiveness in mice
19. + T-lymphocytes and interleukin-5 mediate antigen-induced eosinophil infiltration into the mouse trachea
20. T-cell-dependent accumulation of eosinophils in the lung and its inhibition by monoclonal anti-interleukin-5
21. Suplatast tosilate, a new type of antiallergic agent, prevents the expression of airway hyperresponsiveness in guinea pigs
22. Effects of Y-24180, a receptor antagonist to platelet-activating factor, on allergic cutaneous eosinophilia in mice
23. 1-W/W(v) mice
24. Inhibition of vascular permeability increase in mice: An additional anti-allergic mechanism of glucocorticoids
25. The effect of corticosteroids on monocyte and neutrophil activation in bronchial asthma
26. Prednisone inhibits the appearance of inflammatory mediators and the influx of eosinophils and basophils associated with the cutaneous late-phase response to allergen
27. Effect of topical cromoglycate solution on atopic dermatitis: Combined treatment of sodium cromoglycate solution with the oral anti-allergic medication, oxatomide
28. Chronic urticaria
29. The treatment of asthma