Effects of subacutely administered saiboku-to, an oriental herbal medicine, on pharmacodynamics and pharmacokinetics of diazepam in rodents

European Journal of Drug Metabolism and Pharmacokinetics

Volumn 25, Issue 2, 2000, Pages 127-136

  Yuzurihara, M ^a   Ikarashi, Y ^b   Ishihara, K ^a   Kushida, H ^a   Ishige, A ^a   Sasaki, H ^a   Maruyama, Y ^b  

^a Kampo and Pharmacognosy Laboratories   (Japan)

^b GUNMA UNIVERSITY   (Japan)

Author keywords

Anxiolytic like effect; Cytochrome P 450; Diazepam; Drug metabolizing enzyme; Saiboku to

Indexed keywords

ANTICONVULSIVE AGENT; ANXIOLYTIC AGENT; DIAZEPAM; HERBACEOUS AGENT; HYPNOTIC AGENT; MUSCLE RELAXANT AGENT; SAIBOKU TO; SEDATIVE AGENT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BLOOD LEVEL; DRUG MECHANISM; DRUG METABOLISM; DRUG POTENTIATION; DRUG PROTEIN BINDING; ENZYME INHIBITION; MALE; MUSCLE RELAXATION; NONHUMAN; PHARMACODYNAMICS; RAT; SEDATION; TRANQUILIZING ACTIVITY;

ANIMALS; ANTI-ANXIETY AGENTS; CALCIUM; CYTOCHROME P-450 ENZYME SYSTEM; DIAZEPAM; DRUG SYNERGISM; DRUGS, CHINESE HERBAL; LIVER; MALE; MEDICINE, KAMPO; MICE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A;

EID: 0033679216     PISSN: 03787966     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF03190079     Document Type: Article

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