Repolarization changes in a double-blind crossover study of dofetilide versus sotalol in the treatment of ventricular tachycardia

PACE - Pacing and Clinical Electrophysiology

Volumn 23, Issue 11 II, 2000, Pages 1935-1938

  Boriani, Giuseppe ^a   Biffi, Mauro ^a   De Simone, Nicola ^a   Bacchi, Letizia ^a   Martignani, Cristian ^a   Bitonti, Federica ^b   Zannoli, Romano ^a   Butrous, Ghazwan ^b   Branzi, Angelo ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b Pfizer Research   (United Kingdom)

Author keywords

Antiarrhythmic drugs electrophysiological study; QT dispersion; Repolarization; Ventricular tachycardia

Indexed keywords

DOFETILIDE; SOTALOL;

ADULT; AGED; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGY; FEMALE; HEART VENTRICLE TACHYCARDIA; HUMAN; MAJOR CLINICAL STUDY; MALE; QT INTERVAL; RANDOMIZED CONTROLLED TRIAL;

ANTI-ARRHYTHMIA AGENTS; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; ELECTROCARDIOGRAPHY; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; PHENETHYLAMINES; SOTALOL; SULFONAMIDES; TACHYCARDIA, VENTRICULAR; TREATMENT OUTCOME;

EID: 0033674989     PISSN: 01478389     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1540-8159.2000.tb07056.x     Document Type: Article

References (23)

1. Sotalol for ventricular tachyarrhythmias: Beta-blocking and Class III contributions, and relative efficacy versus Class I drugs after prior drug failure
2. Prevention of implantable-defibrillator shocks by treatment with sotalol
3. Sotalol
4. A novel potent and highly selective Class III antiarrhythmic agent which blocks potassium channels in cardiac cells
5. Dofetilide
6. + current in cardiac myocytes by dofetilide
7. Dofetilide in patients with congestive heart failure and left ventricular dysfunction
8. Electrocardiographic indexes of dispersion of ventricular repolarisation: An isolated heart validation study
9. Will QT dispersion play a role in clinical decision making?
10. QT dispersion and inducibility of ventricular tachycardia during programmed electrical stimulation
11. QT dispersion in nonsustained ventricular tachycardia and coronary artery disease
12. Precordial QT dispersion and inducible ventricular tachycardia
13. Antiarrhythmic drug effects on QT interval dispersion in patients undergoing electropharmacologic testing for ventricular tachycardia and fibrillation
14. A double blind multicentre cross over study on dofetilide versus sotalol in patients with inducible sustained ventricular tachycardia and coronary heart disease
15. An analysis of the time relationship of the electrocardiogram
16. Dispersion of ventricular repolarisation
17. QT dispersion and sudden unexpected death in chronic heart failure
18. QT dispersion and risk factors for sudden cardiac death in patients with hypertrophic cardiomyopathy
19. Reduction in QT dispersion by sotalol following myocardial infarction
20. Precordial QT interval dispersion as a marker of torsade de pointes
21. Effects of amiodarone, sematilide, and sotalol on QT dispersion
22. Effect of amiodarone on QT dispersion in the 12-lead standard electrocardiogram and its significance for subsequent arrhythmic events
23. Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: Prospective comparison of sotalol versus quinidine