Preliminary contribution to the complex reduction processes involving mitomycin C

Electroanalysis

Volumn 12, Issue 12, 2000, Pages 952-959

  Zuman, Petr ^a   Pérez, Pedro ^b   Marín, Dolores ^b  

^a CLARKSON UNIVERSITY   (United States)

^b UNIVERSITY OF ALCALÁ   (Spain)

Author keywords

Acid catalyzed; Hydrolytic activation; Mitomycin C; Reductive activation

Indexed keywords

CATALYSIS; REDUCTION;

ACID CATALYZED; ELECTROCHEMICAL STUDIES; HYDROLYTIC ACTIVATION; HYDROLYTIC PROCESS; MITOMYCIN C; NEGATIVE POTENTIAL; POTENTIAL RANGE; QUINONOIDS; REDUCTION PROCESS; REDUCTIVE ACTIVATION;

CHEMICAL ACTIVATION;

1,4 BENZOQUINONE; ACID; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; DNA; GUANINE; HYDROQUINONE; MITOMYCIN; QUINONE DERIVATIVE;

ARTICLE; CATALYSIS; CHEMICAL REACTION KINETICS; DNA DRUG COMPLEX; DRUG HYDROLYSIS; ELECTRIC POTENTIAL; ELECTROCHEMISTRY; PH; REDUCTION;

EID: 0033672082     PISSN: 10400397     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4109(200008)12:12<952::AID-ELAN952>3.0.CO;2-J     Document Type: Article

References (8)

1. I.V. Iyer, W. Szybalski, Science 1964, 145, 55.
2. W.A. Remers, The Chemistry of Antitumor Antibiotics, Vol. 2, Wiley, New York 1979, p. 221.
3. R.W. Franck, M. Tomasz, in The Chemistry of Antitumor Agents (Ed: D.E.V. Wilman), Blackie, Glasgow 1990, p. 379.
4. M. Tomasz, in Molecular Basis of Drug-DNA Antitumor Action (Eds: S. Neidle, M.J. Waring), Macmillan, London 1993, p. 312.
5. S.K. Carter, S.T. Crooke, Mitomycin C. Current Status and New Developments, Academic Press, New York 1979.
6. S.T. Crooke, W.T. Bradner, Cancer Treat. Rev. 1976, 3, 121.
7. M. Tomasz, R. Lipman, D. Chowdary, J. Pawlak, G.L. Verdine, K. Nakanishi, Science 1987, 236, 1204.
8. M.F. Weidner, J.T. Millard, P.B. Hopkins, J. Am. Chem. Soc. 1989, 111, 9270.