Utility of A-Mel-3 tumoral cell line on the cytotoxic assessment of heavy metals;Utilidad de la linea celular de origen tumoral A-Mel-3 en la evaluacion de la citotoxicidad por metales pesados

Revista de Toxicologia

Volumn 17, Issue 3, 2000, Pages 133-139

  Romero Garcia, D ^a   Gomez Zapata, M ^a   Luna, A ^a   Garcia Fernandez, A J ^a  

^a UNIVERSITY OF MURCIA   (Spain)

Author keywords

A Mel 3; Cadmium; Cytotoxicity; Mercury; Morphological characterisation; Tumoral cell line

Indexed keywords

CADMIUM; HEAVY METAL; MERCURY; NEUTRAL RED;

ARTICLE; CELL ORGANELLE; CELL SWELLING; CELL ULTRASTRUCTURE; CYTOTOXICITY; DRUG UPTAKE; EXPOSURE; LETHAL DOSE; TOXICITY TESTING; TUMOR CELL LINE;

EID: 0033671019     PISSN: 02127113     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (53)

1. 2+-Induced kidney necrosis
2. Electron microscopy study of cadmium neprhotoxicity in the rat
3. Acute mercuric chloride nephrotoxicity. An electron microscopic and metabolic study
4. Ultrastructural changes in renal proximal tubules after chronic organic and inorganic mercury intoxication
5. Ultrastructural study of nephritis induced in Brow Norway rats by mercury chloride
6. Mitochondria alterations in Cd-treated rats. General regression of inner membrane cristae and electron transport impairment
7. Acute cadmium chloride-induced renal toxicity in the Syrian hamster
8. Changes in the nucleoli of ephitelial cells of the kidney tubules in mercuric chloride-induced experimental kidney tubular necrosis
9. Morpho-logical effects of cadmium on proximal tubular cells in rats
10. Effect of cadmium and/or selenium on liver mitochondria and rough endoplasmic reticulum in the rat
11. Captopril protection from the nephrotoxic effects of mercury
12. La productividad cientifica espa-nola en relacion con metodos experimentales alternativos in vivo e in vitro
13. An improved technique for massive tissue culture
14. Cytotoxicity of manganese for mammalian cells in vitro comparisons with lead, mercury and cadmium
15. Comparison of cytotoxicity of mercury-selenium and mercury compounds on cultured cells
16. High temperature enhances cytotoxicity of mercury (HgC12) on HeLa S3 cells
17. A simple quantitative procedure using monolayer culture for cytotoxicity assays (HTD/NR-90)
18. Toxicity determined in vitro by morphological alterations and neutral red absorptions
19. Ultrastructure of the hamster melanoma A Mel 3 of Fortner
20. Cellular distribution of inorganic mercury and its relation to cytotoxicity in bovine kidney cell cultures
21. Mercuric chloride affects protein secretion in rat primary hepatocytes cultures: A biochemical ultrastructural, and gold immunocytochemical study
22. Cytotoxicity of gallium and indium ions compared with mercuric ion
23. Cadmium and mercury toxicity in a human fetal hepatic cell line (WRL-68 cells)
24. Cadmium induces apoptosis in a human T cell line
25. Inorganic mercury chloride-induced apoptosis in the cultured porcine renal cell line LLC-PK1
26. Sex difference of mercuric chloride-induced renal tubular necrosis in rats from the aspect of sex differences in renal mercury concentration and sulfhydryl levels
27. Electron microscopic and radioautographic study of DNA synthesis in kidney tubule ephitelial cells in white rats with sublimate-induced necronephrosis
28. High dietary protein regimens provide significant protection from mercury nephrotoxicity in rats
29. Effect of L-ascorbic acid pretreatment on cadmium toxicity in the male Fischer (F344/NCr) rat
30. Nephrotoxicity of re-peated injections of cadmium-metallothionein in rats
31. Metal accumulation and nephron heterogeneity in mercuric chloride-induced acute renal failure
32. Comparative biochemical effects of low doses of mercury II chloride in the F344 rat and the multimammate mouse (Mastomys natalensis)
33. Suppression of Kupffer cell function prevents cadmium induced hepatocellular necrosis in the male Sprague-Dawley rat
34. Effects of mercuric chloride on the membrane integrity of cultured cell lines
35. Cytotoxicity and accumulation of Hg, Ag, Cd, Cu, Pb and Zn in human peripheral T and B lymphocytes and monocytes in vitro
36. Low concentrations of mercury induce changes in ion composition of cultured myoblasts
37. Altered membrane skeleton of red blood cells participates in cadmium-induced anemia
38. Time course of cadmium-induced ultrastructural changes in rat liver
39. Electron microscopic study of the cytotoxicity of cadmium and mercury in vitro
40. In vitro analysis of the accumulation and toxicity of inorganic mercury in segments of the proximal tubule isolated from the rabbit kidney
41. Differential cytotoxicity of cadmium to rat embryonic fibroblasts and human skin fibroblasts
42. Evolucion de la citotoxicidad in vitro de insecticidas organoclorados y metales en la linea CHO-K1 usando cuatro metodos alternativos
43. Studies on cytotoxic and genotoxic effects of cadmium nitrate and lead nitrate in Chinese Hamster Ovary cells
44. Cytotoxicity of heavy metals in the human small intestinal epithelial cell line I-407: The role of glutation
45. Evaluacion de la citotoxicidad de metales in vitro en las lineas celulares de peces BF-2 y RTG-2 por dos metodos alternativos
46. In vitro cytotoxicity testing of aquatic pollutants (cadmium, copper, zinc, nickel) using established fish cell lines
47. Cytotoxicity of mercury compounds in LLC-PK1, MDCK and human proximal tubular cells
48. In vitro cyto- and genotoxicity of organomercurials to cells in culture
49. Primary cultures of rabbit renal proximal tubule cells III. Comparative cytotoxicity of inorganic and organic mercury