Update on the MEN 2A c804 RET mutation: Is prophylactic thyroidectomy indicated?

Surgery

Volumn 128, Issue 6, 2000, Pages 1052-1058

  Frohnauer, Mary K ^a,b   Decker, Ruth A ^a,b  

^a MAINE MEDICAL CENTER   (United States)

^b Decker Foundation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN;

ADOLESCENT; ADULT; ARTICLE; CHILD; CHROMOSOME 10Q; CLINICAL ARTICLE; FEMALE; GENETIC ANALYSIS; GENETIC CODE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; PEDIGREE ANALYSIS; PENETRANCE; PRIORITY JOURNAL; SIPPLE SYNDROME; SURGICAL RISK; THYROIDECTOMY;

EID: 0033670409     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1067/msy.2000.11/6/111080     Document Type: Article

References (17)

1. Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2a
2. Mutations in the RET proto-oncogene are associated with MEN 2a and FMTC
3. Occurrence of MEN 2a in familial Hirschsprung's disease: A new indication for genetic testing of the RET proto-oncogene
4. RET mutations in exons 13 and 14 of FMTC patients
5. A codon 891 exon 15 RET proto-oncogene mutation in familial medullary thyroid carcinoma: A detection strategy
6. Progress in genetic screening of multiple endocrine neoplasia type 2A: Is calcitonin testing obsolete?
7. Prophylactic surgery for multiple endocrine neoplasia type IIa after genetic diagnosis: Is parathyroid transplantation indicated?
8. Distinction between sporadic and hereditary medullary thyroid carcinoma (MTC) by mutation analysis of the RET proto-oncogene
9. A GTG to ATG novel point mutation at codon 804 in exon 14 of the RET proto-oncogene in two families affected by familial medullary thyroid carcinoma
10. Familial medullary thyroid carcinoma: Presymptomatic diagnosis and management in children
11. Detection of RET mutations in muhiple endocrine neoplasia type 2a and familial medullary thyroid carcinoma by denaturing gradient gel electrophoresis
12. Specific mutations of the RET proto-oncogene are related to disease phenotype in MEN 2A and FMTC
13. The relationship between specific RET proto-oncogene mutations and disease phenotype in multiple endocrine neoplasia type 2
14. Hirschsprung disease in MEN 2A: Increased spectrum of RET exon genotypes and strong genotype-phenotype correlation
15. The clinical and screening age-at-onset distribution for MEN-2 syndrome
16. Testing children for cancer genes: The rule of earliest onset
17. Provocative agents and the diagnosis of medullary thyroid carcinoma of the thyroid gland