Preservation of collagen-induced whole blood platelet aggregation by tranexamic acid therapy in primary cardiac valve surgery

Perfusion

Volumn 15, Issue 6, 2000, Pages 507-513

  Miyashita, T ^a   Kamibayashi, T ^a   Ohnishi, Y ^a   Kobayashi, J ^a   Kuro, M ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; D DIMER; EDETIC ACID; FENTANYL; FIBRINOGEN; HEPARIN; ISOFLURANE; MIDAZOLAM; MORPHINE; OXYGEN; PROTAMINE; SCOPOLAMINE; TRANEXAMIC ACID; VECURONIUM;

ADULT; AGED; ANESTHESIA INDUCTION; ARTICLE; BOLUS INJECTION; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTINUOUS INFUSION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; FEMALE; FIBRINOLYSIS; HEART VALVE SURGERY; HEMOSTASIS; HUMAN; MALE; PEROPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; THROMBOCYTE AGGREGATION; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION;

ADULT; ANTIFIBRINOLYTIC AGENTS; BLOOD LOSS, SURGICAL; CARDIOPULMONARY BYPASS; COLLAGEN; FEMALE; HEART VALVES; HEMOSTASIS; HUMANS; INTRAOPERATIVE COMPLICATIONS; MALE; MIDDLE AGED; PLATELET AGGREGATION; TRANEXAMIC ACID;

EID: 0033669284     PISSN: 02676591     EISSN: None     Source Type: Journal    
DOI: 10.1177/026765910001500606     Document Type: Article

References (20)

1. Management of coaglopathy associated with cardiopulmonary bypass
2. Platelet function and cardiopulmonary bypass
3. Platelet function during cardiac operation
4. Relationship of fibrinolysis and platelet function to bleeding after cardiopulmonary bypass
5. Comparison of the effects of aprotinin and tranexamic acid on blood loss and related variables after cardiopulmonary bypass
6. Effect of aprotinin on need for blood transfusion after repeat open heart surgery
7. Changes in coaglation patterns, blood loss and blood use after cardiopulmonary bypass: Aprotinin vs tranexamic acid vs epsilon aminocaproic acid
8. Aprotinin protects platelets against the initial effect of cardiopulmonary bypass
9. Haemostasis in patients indergoing extracorporeal circulation: The effect of aprotinin (Trasylol)
10. Platelet-rich plasma reduces postoperative blood loss after cardiopulmonary bypass
11. Prophylactic tranexamic acid and ε-aminocaproic acid for primary myacardial revascularization
12. Tranexamic acid is effective in decreasing postoperative bleeding and transfusions in primary coronary artery bypass operations: A double-blind, randomized, placebo-controlled trial
13. Tranexamic acid and aprotinin reduce postoperative bleeding and transfusions during primary coronary revascularization
14. Proteolysis of platelet glycoprotein Ib by plasmin is facilitated by plasmin lysine-binding regions
15. Activation of plasminogen by tissue plasminogen activator on normal and thrombasthenic platelets: Effects on surface proteins and platelet aggregation
16. Successful use of a reduced dose of protamine after cardiopulmonary bypass
17. Prophylatic administration of tranexamic acid preserves platelet numbers during extracorporeal circulation in rabbit
18. Effect of tranexamic acid on platelet ADP during extracorporeal circulation
19. The effect of tranexamic acid on bleeding time and hemostasis
20. Prevalence of anaphylactic reactions to aprotinin: Analysis of two hundred and forty-eight re-exposures to aprotinin in heart operations