From telomeres to T-antigens: Many roads... multiple pathways... novel associations in the search for the origins of human gliomas

Annals of Neurology

Volumn 48, Issue 6, 2000, Pages 823-825

  Major, Eugene O ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCINE CLEAVAGE SYSTEM; PROTEIN P53; RETINOBLASTOMA PROTEIN; TELOMERASE; VIRUS T ANTIGEN;

CARCINOGENESIS; CELL CYCLE; GLIOMA; HUMAN; JC VIRUS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; SIMIAN VIRUS 40; TELOMERE;

ANTIGENS, VIRAL, TUMOR; BRAIN NEOPLASMS; GLIOMA; HUMANS; PROGNOSIS; TELOMERE;

EID: 0033668568     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(200012)48:6<823::AID-ANA1>3.0.CO;2-0     Document Type: Review

References (15)

1. Creation of human tumor cells with defined genetic elements
2. Correlation of clinical features and telomerase activity in human gliomas
3. Telomere shortening triggers a p53-dependent cell cycle arrest via accumulation of G rich single stranded DNA fragments
4. Anti-sense telomerase therapy suppressed glioma proliferation
5. Cell cycle: Piecing together the p53 puzzle
6. New insights into the mechanism of inhibition of p53 by simian virus 40 large T antigen
7. Reactivation of human neurotropic JC virus expressing oncogenic proteins in a recurrent glioblastoma multiforme
8. Brain tumors in owl monkeys inoculated with a human polyomavirus (JCV)
9. Owl monkey astrocytoma cells in culture spontaneously produce infectious JC virus which demonstrates altered biological properties
10. Transcriptional regulation: Lessons from the human neurotropic polyomavirus, JCV
11. Identification and classification of p53 regulated genes
12. Hypothesis: 'Rogue cell' type chromosomal damage in lymphocytes is associated with infection with the human JC human polyomavirus and has implications for oncogenesis
13. Simian virus 40 (SV40): A possible human polyomavirus