Pharmacokinetics of ofloxacin enantiomers after intravenous administration for antibiotic prophylaxis in biliary surgery

Journal of Clinical Pharmacology

Volumn 40, Issue 8, 2000, Pages 869-874

  Gascon, A R ^a   Campo, E ^b   Hernandez, R M ^a   Calvo, B ^a   Errasti, J ^b   Pedraz Munoz, J L ^a  

^a UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^b HOSPITAL TXAGORRITXU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOFLOXACIN; OFLOXACIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT;

ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; AREA UNDER THE CURVE; ARTICLE; BILIARY TRACT DISEASE; BILIARY TRACT SURGERY; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG TISSUE LEVEL; ENANTIOMER; ESCHERICHIA COLI; FEMALE; HUMAN; MALE; MINIMUM INHIBITORY CONCENTRATION; STEREOCHEMISTRY; SURGICAL INFECTION;

EID: 0033668379     PISSN: 00912700     EISSN: None     Source Type: Journal    
DOI: 10.1177/00912700022009602     Document Type: Article

References (20)

1. In vitro antibacterial activity of DR-3355, the S-(-) isomer of ofloxacin
2. Synthesis and antibacterial activities of optically active ofloxacin
3. In vitro and in vivo antibacterial activities of levofloxacin (l-ofloxacin), an optically active ofloxacin
4. Levofloxacin: A review of its antibacterial activity, pharmacokinetics and therapeutics efficacy
5. Levofloxacin: Its use in infections of the respiratory tract, skin, soft tissues and urinary tract
6. Role of quinolones in surgical prophylaxis
7. Pharmacokinetics and tissue distribution of intravenous ofloxacin for antibiotic prophylaxis in biliary surgery
8. Rapid stereospecific high-performance liquid chromatographic determination of levofloxacin in human plasma and urine
9. Noncompartmental analysis based on statistical moment theory
10. Species-related stereoselective disposition of ofloxacin in the rat, dog and monkey
11. Enantioselective disposition of ofloxacin in humans
12. Pharmacodynamic of fluoroquinolones
13. Pharmacodynamics of intravenous ciprofloxacin in seriously ill patients
14. Pharmacodynamics and pharmacokinetics of antibiotics with special reference to the fluoroquinolones
15. Pharmacodynamics of levofloxacin: A new paradigm for early clinical trials
16. The importance of pharmacokinetic/pharmacodynamic surrogate markers to outcome-focus on antimicrobial agents
17. Pharmacokinetic profile of levofloxacin following once-daily 500-milligram oral or intravenous doses
18. Pharmacokinetics and clinical results of parenterally administered new quinolones in humans
19. Role of antimicrobial pharmacokinetics and pharmacodynamics in surgical prophylaxis