Detection of the causal mutation for canine leukocyte adhesion deficiency (CLAD) using pyrosequencing

Animal Genetics

Volumn 31, Issue 5, 2000, Pages 326-328

  Kijas, J M H ^a   Juneja, R K ^a   Gafvert, S ^a   Andersson, L ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

CD18; CLAD; ITGB2; Pyrosequencing

Indexed keywords

BREED; DISEASE DETECTION; GENE LOCUS; GENE MUTATION; GENETIC POLYMORPHISM; HETEROZYGOSITY; LEUKOCYTE ADHERENCE; MISSENSE MUTATION; NUCLEOTIDE SEQUENCE; PYROSEQUENCING;

ANIMALS; ANTIGENS, CD18; BASE SEQUENCE; DOG DISEASES; DOGS; EUROPE; HETEROZYGOTE DETECTION; LEUKOCYTE-ADHESION DEFICIENCY SYNDROME; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL;

EID: 0033665626     PISSN: 02689146     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2052.2000.00650.x     Document Type: Article

References (12)

1. The severe and moderate phenotypes of heritable Mac-1, LFA-1 deficiency: Their quantitative definition and relation to leukocyte dysfunction and clinical features
2. Point mutations impairing cell surface expression of the common beta subunit (CD18) in a patient with leukocyte adhesion molecule (Leu-CAM) deficiency
3. Oligonucleotide ligation assay (OLA) for the diagnosis of familial hypercholesterolemia
4. Genome wide mapping with biallelic markers in Arabidopsis thaliana
5. A missense mutation in the β-2 integrin gene (ITGB2) causes canine leukocyte adhesion deficiency
6. A ligase-mediated gene detection technique
7. Leukocyte adhesion deficiency: Identification of novel mutations in two Japanese patients with a severe form
8. Direct analysis of single-nucleotide polymorphism on double-stranded DNA by pyrosequencing
9. Canine granulocytopathy syndrome: Neutrophil dysfunction in a dog with recurrent infections
10. Real-time pyrophosphate detection for DNA sequencing
11. Identification and prevalence of a genetic defect that causes leukocyte adhesion deficiency in Holstein cattle
12. Leucocyte adhesion protein deficiency in Irish setter dogs