Critical base substitutions that affect the splicing and/or homing activities of the group I intron bi2 of yeast mitochondria

Molecular and General Genetics

Volumn 264, Issue 1-2, 2000, Pages 137-144

  Szczepanek, T ^a   Jamoussi, K ^a   Lazowska, J ^a  

^a CNRS   (France)

Author keywords

Group I intron; Intronic protein mutations; Maturase Homing endonuclease; Mitochondria; Yeast

Indexed keywords

ENDONUCLEASE; M PROTEIN; NUCLEIC ACID BASE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; INTRON; MISSENSE MUTATION; MITOCHONDRION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL; RNA SPLICING; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

SACCHAROMYCES; SACCHAROMYCES CAPENSIS;

EID: 0033660096     PISSN: 00268925     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004380000297     Document Type: Article

References (41)

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11. Crystal structure of PI-SceI endonuclease with protein splicing activity
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14. In vitro splicing of the terminal intervening sequence of Saccharomyces cerevisiae cytochrome b pre-mRNA
15. Substitutions in conserved dodecapeptide motifs that uncouple the DNA cleavage activities of PI-SceI endonuclease
16. The structure of I-CreI, a group 1 intron-encoded homing endonuclease
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18. The maturase encoded by a group I intron from Aspergillus nidulans stabilizes RNA tertiary structure and promotes rapid splicing
19. A protein encoded by a group I intron in Aspergillus nidulans directly assists RNA splicing and is a DNA endonuclease
20. Protein splicing removes intervening sequences in an archea DNA polymerase
21. Homing endonucleases: Structure, function and evolution
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27. Sequence of introns and flanking exons in wild-type and box3 mutants reveals an interlaced splicing protein coded by an intron
28. Protein encoded by the third intron of cytochrome b gene in Saccharomyces cerevisiae is an mRNA maturase. Analysis of mitochondrial mutants, RNA transcripts, proteins and evolutionary relationships
29. Two homologous mitochondrial introns from closely related Saccharomyces species differ by only a few amino acid replacements in their open reading frames: One is mobile, the other is not
30. Homing of a group II intron in yeast mitochondrial DNA is accompanied by unidirectional co-conversion of upstream-located markers
31. Purification and characterization of the DNA cleavage and recognition site of I-ScaI mitochondrial group I intron encoded endonuclease produced in Escherichia coli
32. Alteration of the Saccharomyces cerevisiae COX2 mRNA 5'-untranslated leader by mitochondrial gene replacement and functional interaction with the translational activator protein PET111
33. Function of intron-encoded proteins from yeast mitochondrial genome. RNA maturase and DNA endonuclease
34. A mitochondrial group-I intron in fission yeast encodes a maturase and is mobile in crosses
35. Genetic analysis of the Chlamydomonas reinhardtii I-CreI mobile intron homing system in Escherichia coli
36. Crystal structure of the thermostable archaeal intron-encoded endonuclease I-Dmo1
37. Replacement of two non-adjacent amino acids in the S. cerevisiae bi2 intron-encoded RNA maturase is sufficient to gain a homing-endonuclease activity
38. Two homologous introns from related Saccharomyces species differ in their mobility
39. Evolutionarily conserved and functionally important residues in the I-Ceu1 homing endonuclease
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41. A latent intron-encoded maturase is also an endonuclease needed for intron mobility