Relationships between psychotropic drug dosage, plasma drug concentration, and prolactin levels in nursing home residents

Therapeutic Drug Monitoring

Volumn 22, Issue 6, 2000, Pages 688-694

  Cohen Mansfield, Jiska ^a,b   Taylor, Levi ^a   Woosley, Raymond ^c   Lipson, Steven ^a   Werner, Perla ^d   Billig, Nathan ^c  

^a Hebrew Home of Greater Washington   (United States)

^b GEORGE WASHINGTON UNIVERSITY MEDICAL CENTER   (United States)

^c GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF HAIFA   (Israel)

Author keywords

Aging; Drug metabolism; Haloperidol; Lorazepam; Thioridazine

Indexed keywords

HALOPERIDOL; LORAZEPAM; PROLACTIN; PSYCHOTROPIC AGENT; THIORIDAZINE;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG WITHDRAWAL; FEMALE; HUMAN; MALE; NURSING HOME; PRIORITY JOURNAL; PROLACTIN RELEASE; RANDOMIZED CONTROLLED TRIAL; STEADY STATE;

AGED; AGED, 80 AND OVER; ANTI-ANXIETY AGENTS; ANTIPSYCHOTIC AGENTS; CROSS-OVER STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HALOPERIDOL; HUMANS; LORAZEPAM; MALE; NURSING HOMES; PLACEBOS; PROLACTIN; THIORIDAZINE; TRANQUILIZING AGENTS;

EID: 0033659825     PISSN: 01634356     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007691-200012000-00007     Document Type: Article

References (28)

1. Psychotropic drug practice in nursing homes
2. Neuroleptic prescriptions for acutely ill geriatric patients
3. Haloperidol and the geriatric patient: Practical considerations
4. Rational use of psychoactive drugs in the geriatric patient
5. Pharmacological treatment of agitation in a nursing home
6. Prescribing of psychotropics in elderly nursing home patients
7. Clinical pharmacokinetics of anxiolytics and hypnotics in the elderly. Therapeutic considerations (Part I)
8. Pharmacokinetics of haloperidol in man
9. Single dose kinetics of thioridazine and its two psychoactive metabolites: A dose proportionality study
10. Antipsychotic drugs
11. Plasma haloperidol and reduced haloperidol concentrations in a geriatric population
12. Absence of age effect on plasma haloperidol neuroleptic levels in psychiatric patients
13. Metabolism of thioridazine in the elderly
14. Plasma levels and half lives of thioridazine and some of its metabolites
15. Serum neuroleptic concentrations and tardive dyskinesia
16. Theoretical and therapeutic considerations for the anxiety disorders
17. Effect of age and cardiopulmonary bypass on the pharmacokinetics of lorazepam
18. Treatment of anxiety in the elderly
19. Management of psychotropic-induced hyperprolactinemia
20. Defective N-oxidation of sparteine in man: A new pharmacogenic effect
21. Diazepam: Endocrine effects and hypothalamic binding sites in the developing male and female rat
22. Withdrawal of haloperidol, thioridazine and lorazepam in the nursing home
23. The brief cognitive rating scale (BCRS): Findings in primary degenerative dementia (PPD)
24. Measurement of haloperidol in human breast milk by high performance liquid chromatography
25. Lorazepam kinetics in the elderly
26. Haloperidol concentrations in patients with Alzheimer's dementia