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Volumn 48, Issue 11, 2000, Pages 1667-1672

Studies on 8-methoxyquinolones: Synthesis and antibacterial activity of 7-(3-amino-4-substituted)pyrrolidinyl derivatives

(7) Kawakami, K a Takahashi, H a Ohki, H a Kimura, K a Miyauchi, S a Miyauchi, R a Takemura, M a

a DAIICHI SANKYO CO (Japan)

Author keywords

3 amino 4 fluoromethylpyrrolidine; 8 methoxyquinolone; An tibacterial activity; Lipophilicity; Micronuclei formation; Single intravenous toxicity

Indexed keywords

CIPROFLOXACIN; LEVOFLOXACIN; NORFLOXACIN; PYRROLIDINE DERIVATIVE; QUINOLINE DERIVATIVE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SITAFLOXACIN; SPARFLOXACIN; TOSUFLOXACIN;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; DRUG BLOOD LEVEL; DRUG POTENCY; DRUG SYNTHESIS; GENOTOXICITY; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

EID: 0033659193 PISSN: 00092363 EISSN: None Source Type: Journal
DOI: 10.1248/cpb.48.1667 Document Type: Article

Times cited : (22)

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