Cyclosporine A and Cremophor EL induce contractions of human saphenous vein: Involvement of thromboxane A2 receptor-dependent pathway

Journal of Cardiovascular Pharmacology

Volumn 36, Issue 6, 2000, Pages 693-698

  Hardy, Gaëlle ^a   Stanke Labesque, Françoise ^a   Deveaux, Géraldine ^a   Devillier, Philippe ^b   Sessa, Carmine ^c   Bessard, Germain ^a  

^a School of Medicine   (France)

^b HÔPITAL MAISON BLANCHE   (France)

^c HÔPITAL MICHALLON   (France)

Author keywords

Cremophor EL; Cyclosporine A; Human; Saphenous vein; Thromboxane A2 receptor

Indexed keywords

CREMOPHOR; CYCLOSPORIN A; DOCEBENONE; INDOMETACIN; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR; VAPIPROST;

ARTICLE; BLOOD VESSEL REACTIVITY; DRUG EFFECT; HUMAN; HUMAN TISSUE; HYPERTENSION; NEPHROTOXICITY; PRIORITY JOURNAL; SAPHENOUS VEIN;

EID: 0033658167     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200012000-00002     Document Type: Article

References (39)

1. Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders
2. Cyclosporine-associated chronic nephropathy
3. Incidence of hypertension after marrow transplantation among 112 patients randomised to either cyclosporine or methotrexate as graft-versus-host disease prophylaxis
4. Mechanism of cyclosporine-induced hypertension
5. Effet de la ciclosporine A sur la reactivite du reseau vasculaire pulmonaire chez le chien
6. Dose-dependent effect of cyclosporine on renal arterial resistance in dogs
7. Induction of contraction in isolated aorta by cyclosporine
8. Role of nitric oxide in cyclosporine A-induced hypertension
9. 2/prostaglandin endoperoxide receptor antagonist ifetroban
10. Cyclosporin A and cremophor-EL augment renal vascular response to various agonists and nerve stimulation
11. Acute cyclosporine-induced renal vasoconstriction is mediated by endothelin-1
12. Endothelin mediates the renal vasoconstriction induced by cyclosporine in the rat
13. Cyclosporine-induced sympathetic activation and hypertension after heart transplantation
14. Cyclosporine inhibits prostacyclin production by cultured human endothelial cells
15. Cyclosporine suppression of endothelial prostacyclin generation
16. Role of thromboxane and angiotensin in cyclosporine-induced renal vasoconstriction in the dog
17. Cyclosporine-induced coronary artery constriction-dissociation between thromboxane release and coronary vasospasm
18. 2 in rats caused by cyclosporine
19. Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity
20. Cyclosporine A nephrotoxicity: Role of thromboxane and reactive oxygen species
21. Acute effects of intravenous cyclosporine on renal function in healthy humans
22. Effects of polysorbates and Cremophor EL on vascular responses in rat aorta
23. The vasoconstrictor effect of cyclosporine on the pulmonary vein is mediated by its vehicle: The cremophor
24. 2-induced contraction in human internal mammary artery and saphenous vein
25. 2 receptor of human isolated gastroepiploic artery and saphenous vein
26. Vasoconstrictor effects of iso-Prostaglandin F(2α) type-III (8-iso-prostaglandin F(2α)) on human saphenous veins
27. 2 receptor blocking drug on platelets, vascular and airways smooth muscle in vitro
28. 2,3,5-Trimethyl-6-(12 hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone (AA861), a selective inhibitor of the 5-lipoxygenase reaction and the biosynthesis of slow-reacting substance of anaphylaxis
29. Some quantitative uses of drug antagonists
30. Therapeutic range of cyclosporin in renal transplant patients by specific monoclonal radioimmunoassay
31. Cyclosporine-associated neurotoxicity. The need for a better guide for immunosuppressive therapy
32. Cremophor pharmacokinetics in patients receiving 3-, 6-, and 24-hours infusion of Paclitaxel
33. 2+]c increase
34. Cyclosporine A up-regulates angiotensin II receptor and calcium response in human vascular smooth muscle cells
35. Calcium entry blockade may prevent cyclosporin A-induced hypersensitivity to angiotensin II and endothelial dysfunction in the rat aorta
36. Preventive effects of diltiazem on cyclosporin A-induced vascular smooth muscle dysfunction
37. Effect of cyclosporin A and analogues on cytosolic calcium and vasoconstriction: Possible lack of relationship to immunosuppressive activity
38. Endothelin-1 receptor antagonist: Effect on endothelin- and cyclosporine-treated mesangial cells
39. Direct vascular smooth muscle contractile effect of cyclospordn A and its vehicle in rabbit isolated arteries