The uptake, location and fluorescence of hypericin in bovine intact lens

Current Eye Research

Volumn 21, Issue 2, 2000, Pages 597-601

  Sgarbossa, A ^a   Angelini, N ^a   Gioffre, D ^a   Youssef, T ^a   Lenci, F ^a   Roberts, J E ^a  

^a FORDHAM UNIVERSITY   (United States)

Author keywords

Cataracts; Fluorescence; Hypericin; Hypericum; Light therapy; Ocular phototoxicity; St. John's Wort

Indexed keywords

ALCOHOL; ALPHA CRYSTALLIN; BUFFER; DIMETHYL SULFOXIDE; DIPOTASSIUM HYDROGEN PHOSPHATE; HYPERICIN; LENS PROTEIN; POTASSIUM CHLORIDE; SODIUM CHLORIDE;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CATTLE; CHROMATOPHORE; CONTROLLED STUDY; DRUG BINDING; DRUG MONITORING; FLUORESCENCE; HYPERICUM PERFORATUM; LENS; NONHUMAN; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; PRIORITY JOURNAL; PROTEIN BINDING; SPECTROFLUOROMETRY;

EID: 0033653447     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/0271-3683(200008)2121-VFT597     Document Type: Article

References (23)

1. Pharmacological treatment of seasonal affective disorder. The role of hypericum extract
2. Photodynamic inactivation of infectivity of human immunodeficiency virus and other enveloped viruses using hypericin and rose bengal: Inhibition of fusion and sycncytia formation
3. Hypericin inhibits cell growth and induces apoptosis in retinal pigment epithelial cells: Possible involvement of protein kinase C
4. Exposure to bright light and the concurrent use of photosensitizing drugs
5. Ocular phototoxicity
6. Hypericin (active ingredient in St. John's Wort) photooxidation of lens proteins
7. Hypericin inhibits choroidal endothelial cell proliferation and cord formation in vitro
8. Ocular fluorometry: Principles, fluorophores, instrumentation and clinical applications
9. In vivo fluorescence spectrosopy and imaging for oncological applications
10. Detection of porphyrin excited states in the intact bovine lens
11. Photophysical studies on the binding of tetrasulfonatophenylporphyrin to lens proteins
12. Excited-state properties of hypericin : Electronic spectra and fluorescence decay kinetics
13. The mode of chaperoning of dithiothreitol-denaturated α-lactalbumin by α-crystallin
14. Photoeffects on the eye
15. Photodamage to the eye
16. Photochemical mechanisms in cataract formation
17. Reversible increase of photosensitivity by St. John's Wort-extract
18. Hypericum in Seasonal Affective Disorder (SAD)
19. Kinetics and yield of singlet oxygen photosensitized by hypericin in organic and biological media
20. Signaling Pathways in apoptosis induced by PDT with hypericin
21. Improvement of photodynamic therapy by selective protection of normal tissues
22. Improved biometry of the anterior eye segment