Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats. 13) Effects of a single oral dose of cyclophosphamide

Journal of Toxicological Sciences

Volumn 25, Issue SPEC. ISS, 2000, Pages 139-143

  Matsumoto, S ^a   Hirakawa, M ^a   Shimomoto, T ^a   Sato, M ^a   Kitaura, K ^a   Minami, T ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Cyclophosphamide; Quantitative morphometry; Rats; Testicular toxicity

Indexed keywords

CYCLOPHOSPHAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; INTOXICATION; MALE; MALE GENITAL SYSTEM; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; SEMINIFEROUS TUBULE; SPERMATOCYTE; TESTIS INJURY; WEIGHT REDUCTION;

ANIMALIA;

EID: 0033647480     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.25.specialissue_139     Document Type: Article

References (10)

1. Absence of testicular protection by a gonadotropine releasing hormone analogue against cyclophosphamide-induced testicular cytotoxicity in the mouse
2. Aspects of testicular toxicity induced by anti-cancer drugs
3. Sterility and testicular atrophy related to cyclophopsphamide therapy
4. Collaborative assessments of optimal administration period and parameters to detect effects on male fertility in the rat: Effects of cyclophosphamide on the male reproductive system
5. Visual prognosis in Bahcet's disease: Effects of cyclophosphamide and colchicine
6. Cytotoxic effects of chemotherapeutic drugs on mouse testis cells
7. Morphological evaluation of cylophosphamide testicular toxicity in rats using quantitative morphometry of spermatogenic cycle stage
8. Testicular function in prepubertal and pubertal male patients treated with cyclophosphamide for nephrotic syndrome
9. Short-term morphological response of the rat testis to administration of five chemotherapeutic agents