Collaborative work to evaluate toxicity on male reproductive organs by repeated dose studies in rats. 23) A comparative 2- and 4-week repeated oral dose testicular toxicity study of boric acid in rats

Journal of Toxicological Sciences

Volumn 25, Issue SPEC. ISS, 2000, Pages 223-232

  Kudo, S ^a   Tanase, H ^a   Yamasaki, M ^a   Nakao, M ^a   Miyata, Y ^a   Tsuru, K ^a   Imai, S ^a  

^a KYORIN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Boric acid; Crj:Wistar rat; Male reproductive toxicity; Sperm; Testis

Indexed keywords

BORIC ACID;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL DEGENERATION; CONTROLLED STUDY; GIANT CELL; HISTOPATHOLOGY; MALE; MALE GENITAL SYSTEM; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS WEIGHT; TOXICITY TESTING;

ANIMALIA; RATTUS NORVEGICUS; RODENTIA;

EID: 0033647139     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.25.specialissue_223     Document Type: Article

References (11)

1. The reproductive toxicity of boric acid
2. General, reproductive, developmental and endocrine toxicity of boronated compounds
3. Assessment of a short-term reproductive and development toxicity screen
4. The method of sperm motility
5. Testicular toxicity of boric acid(BA): Relationship of dose to lesion development and recovery in the F344 rat
6. Effect of acute exposure to boric acid on the male reproductive system of the rat
7. Utility of a novel chamber for sperm analysis in rats
8. Development of testicular lesions in F344 rats after treatment with boric acid