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Volumn 89, Issue 12, 2000, Pages 1518-1524

Oxidation of HMG-CoA reductase inhibitors by tert-butoxyl and 1,1-diphenyl-2-picrylhydrazyl radicals: Model reactions for predicting oxidatively sensitive compounds during preformulation

Author keywords

1 1 dephenyl 2 picrylhydrazyl radical; Free radicals; HMG CoA reductase inhibitor; Oxidation; Preformulation; Statin; Tert butoxyl radical

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; ANTILIPEMIC AGENT; FREE RADICAL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; SIMVASTATIN; TERT BUTYL ALCOHOL;

EID: 0033638903     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/1520-6017(200012)89:12<1518::AID-JPS2>3.0.CO;2-O     Document Type: Article
Times cited : (13)

References (17)
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    • Kaufman, M.J.1
  • 4
    • 0002552341 scopus 로고
    • Alkoxyl radicals: Radical-molecule reactions
    • Landolt H, Hellwege KH, editors. Numerical data and functional relationships in science and technology, Kinetic constants of radical reactions in fluids, Pt. A: Carbon radicals. Berlin: Springer
    • (1984) , vol.13 , pp. 12-26
    • Scaiano, J.C.1    Howard, J.A.2
  • 7
    • 0024150625 scopus 로고
    • Mechanism of action and biological profile of HMG CoA reductase inhibitors. A new therapeutic alternative
    • (1988) Drugs , vol.36 , pp. 72-82
    • Slater, E.E.1    MacDonald, J.S.2
  • 14
    • 85018823250 scopus 로고    scopus 로고
    • note
  • 15
    • 0000551398 scopus 로고
    • The meaning of the 'polar effect' in hydrogen abstraction by free radicals. Reactions of the tert-butoxy radical
    • (1972) J Am Chem Soc , vol.94 , pp. 7390-7396
    • Zavitsas, A.A.1    Pinto, J.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.