Rapid induction of mild cerebral hypothermia by cold aortic flush achieves normal recovery in a dog outcome model with 20-minute exsanguination cardiac arrest

Academic Emergency Medicine

Volumn 7, Issue 12, 2000, Pages 1341-1348

  Behringer, Wilhelm ^a   Prueckner, Stephan ^a   Safar, Peter ^a   Radovsky, Ann ^a   Kentner, Rainer ^a   Stezoski, S William ^a   Henchir, Jeremy ^a   Tisherman, Samuel A ^b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Cardiac arrest; Cerebral ischemia; Cerebral preservation; Exsanguination; Hemorrhage; Trauma

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA FLOW; ARTICLE; BRAIN INJURY; CARDIOPULMONARY BYPASS; COLD EXPOSURE; CONTROLLED STUDY; DISABILITY; DOG; HEART ARREST; HISTOPATHOLOGY; INDUCED HYPOTHERMIA; INTENSIVE CARE; MALE; NEUROLOGIC EXAMINATION; NONHUMAN; PRIORITY JOURNAL; RESUSCITATION;

ANIMALS; AORTA, THORACIC; AREA UNDER CURVE; BRAIN ISCHEMIA; DISEASE MODELS, ANIMAL; DOGS; HEART ARREST; HEMODYNAMIC PROCESSES; HYPOTHERMIA, INDUCED; IRRIGATION; ISOTONIC SOLUTIONS; MALE; NEUROLOGIC EXAMINATION; RESUSCITATION; SHOCK, HEMORRHAGIC; SODIUM CHLORIDE; SURVIVAL ANALYSIS; TEMPERATURE; TIME FACTORS;

EID: 0033638531     PISSN: 10696563     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1553-2712.2000.tb00489.x     Document Type: Article

References (28)

1. Suspended animation for delayed resuscitation
2. Mechanisms of ischemic brain damage
3. The effect of profound hypothermia on preservation of cerebral ATP content during circulatory arrest
4. The effects of anesthesia and hypothermia on canine cerebral ATP and lactate during anoxia produced by decapitation
5. Cerebral resuscitation from cardiac arrest: Treatment potentials
6. Resuscitation from clinical death: Pathophysiologic limits and therapeutic potentials
7. Hypothermia: Its possible role in cardiac surgery
8. Deep hypothermic circulatory arrest: Current status and future directions
9. Resection of aortic arch aneurysms: A comparison of hypothermic techniques in 60 patients
10. Bloodless surgery by means of profound hypothermia and circulatory arrest. Effect on brain and heart
11. Complete recovery after normothermic hemorrhagic shock and profound hypothermic circulatory arrest of 60 minutes in dogs
12. Profound hypothermia (less than 10 degrees C) compared with deep hypothermia (15 degrees C) improves neurologic outcome in dogs after two hours' circulatory arrest induced to enable resuscitative surgery
13. Emergency cardiopulmonary bypass for resuscitation from prolonged cardiac arrest
14. Hypothermic aortic arch flush for preservation during exsanguination cardiac arrest of 15 minutes in dogs
15. Regional prevalence and distribution of ischemic neurons in dog brains 96 hours after cardiac arrest of 0 to 20 minutes
16. The relationship between directly measured human cerebral and tympanic temperatures during changes m brain temperatures
17. Do standard monitoring sites reflect true brain temperature when profound hypothermia is rapidly induced and reversed?
18. The causes of death in conventional land warfare: Implications for combat casualty care research
19. Civilian gunshot wounds - Outpatient management
20. Future directions for resuscitation research
21. Superior cerebral protection with profound hypothermia during circulatory arrest
22. Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury
23. Peritoneal cooling for mild cerebral hypothermia after cardiac arrest in dogs
24. Comparison of cardiopulmonary resuscitation with cardiopulmonary bypass after prolonged cardiac arrest in dogs. Reperfusion pressures and neurologic recovery
25. Portable and modular cardiopulmonary bypass apparatus and associated aortic balloon catheter
26. Percutaneous initiation of cardiopulmonary bypass
27. Percutaneous intraaortic balloon insertion
28. Complete cerebral recovery after 30 min cardiac arrest (CA) in dogs by preservative cold aortic flush