Current perspectives of biotechnological replacement of insulin secreting cells

Experimental and Clinical Endocrinology and Diabetes

Volumn 108, Issue 8, 2000, Pages 494-497

  Pfeiffer, A F H ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

Author keywords

cell replacement; Genetic engineering; Transplantation

Indexed keywords

BIOTECHNOLOGY; CELL ACTIVATION; CELL DIFFERENTIATION; CELL LINE; EMBRYO CELL; GENETIC MANIPULATION; HUMAN; HUMAN CELL; INSULIN RELEASE; PANCREAS CELL; PANCREAS TRANSPLANTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT SURVEY; STEM CELL;

ANIMALS; BIOTECHNOLOGY; CELL DIFFERENTIATION; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; HUMANS; INSULIN; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; STEM CELLS; TRANSPLANTATION, HETEROLOGOUS;

EID: 0033636870     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2000-11002     Document Type: Short Survey

References (10)

1. Prospects for insulin delivery by ex-vivo somatic cell gene therapy
2. Transplantations in patients with diabetes mellitus
3. Cell-based therapy for insulin-dependent diabetes mellitus
4. Production of mature human insulin by retrovirally engineered fibroblasts and primary hepatocytes
5. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates steptozotocin-induced hyperglycemia
6. Genetic engineering of insulin expression in nonislet-cells: Implications for β-cell replacement therapy for insulin-dependent diabetes mellitus
7. Expressing a human proinsulin cDNA in a mouse ACTH secreting cell
8. Cellular engineering and gene therapy strategies for insulin replacement in diabetes
9. The 'Ulm Zucker Uhr' system and its consequences
10. Gene therapy of diabetes mellitus - Aims, methods and future prospects