A method for radioprobing DNA structures using Auger electrons

International Journal of Radiation Biology

Volumn 76, Issue 12, 2000, Pages 1607-1615

  Nikjoo, H ^a   Laughton, C A ^a   Terrissol, M ^a   Panyutin, I G ^a   Goodhead, D T ^a  

^a MRC Radiation/Genome Stability Unit   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AUGER ELECTRON SPECTROSCOPY; CHROMOSOME BREAKAGE; CHROMOSOME DAMAGE; DNA DAMAGE; DNA PROBE; DNA RECOMBINATION; DNA STRUCTURE; METHODOLOGY; MOLECULAR MODEL; NUCLEAR MAGNETIC RESONANCE; PLASMID; PRIORITY JOURNAL; SYSTEM ANALYSIS; X RAY CRYSTALLOGRAPHY;

EID: 0033636166     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/09553000050201091     Document Type: Article

References (36)

1. Strand breaks in plasmid DNA following positional changes of Auger-electron-emitting radionuclides
2. Models of triple-stranded polynucleotides with optimised stereochemistry
3. The range of high LET effects from 125I decays
4. A method of calculating initial DNA strand breakage following the decay of incorporated 125I
5. Formation of a three-stranded polynucleotide molecule
6. The MIDAS display system
7. Triplex DNA structures
8. Monte Carlo simulation of production of short DNA fragments by low-linear energy transfer radiation using higher-order DNA models
9. Biophysical aspects of Auger processes: A review
10. Clusters of DNA damage induced by ionising radiation: Formation of short DNA fragments. I. Theoretical modelling
11. Structure of d(T)(n)·d(A)(n)·d(T)(n): The DNA triple helix has B-form geometry with C2'-endo sugar pucker
12. Detecting the DNA kinks in a DNA-CRP complex in solution with iodine-125 radioprobing
13. The definition of generalized helicoidal parameters and of axis curvature for irregular nucleic-acids
14. Iodine-125 decay in a synthetic oligodeoxynucleotide. I. Fragment size distribution and evaluation of breakage probability
15. Sugar conformations in intramolecular DNA triplexes determined by coupling constants obtained from automated simulation of P. COSY cross peaks
16. Range of radiochemical damage to DNA with decay of iodine-125
17. Variation of single-strand break yield with scavenger concentration for plasmid DNA irradiated in aqueous solution
18. The formation of phosphate end groups in the radiolysis of polynucleotides in aqueous solution
19. Modelling of Auger-induced DNA damage by incorporated 125I
20. Computational modelling of low energy electron-induced DNA damage by early physical and chemical events
21. Quantitative modelling of DNA damage using Monte Carlo track structure method
22. 125I-labeled oligonucleotides
23. Amber a package of computer-programs for applying molecular mechanics, normal-mode analysis, molecular-dynamics and free-energy calculations to simulate the structural and energetic properties of molecules
24. Simulation of strand break induction by DNA incorporated 125I
25. Low-energy electrons inside active DNA models: A tool to elucidate the radiation action mechanisms
26. Triple helix formation and the antigene strategy for sequence-specific control of gene expression
27. Symmetry and molecular structure of a DNA triple helix: d(T)(n)·d(A)(n)·d(T)(n)·
28. La radiosensibilite envisagee dans ses manifestations generales
29. Chromatin conformation in living cells: Support for a zig-zag model of the 30 nm chromatin fibre
30. Pulse radiolysis of aqueous solutions of deoxyribonucleotides and the DNA: Reaction with hydroxy-radicals
31. Molecular dynamics simulation of the d(T.A.T) triplex helix
32. 125I on a nucleosome
33. A knowledge-based model of DNA hydration
34. Reaction rate of OH radicals with X174 DNA: Influence of salt and scavenger
35. 125I]iodoHoechst 33342: Contribution of scavengeable effects