Selective ß2-adrenoceptor agonist enhances sensitivity to cisplatin in non-small cell lung cancer cell line

Oncology Reports

Volumn 7, Issue 1, 2000, Pages 49-52

  Bando, Takuma ^a,b   Fujimura, Masaki ^b   Kasahara, Kazuo ^b   Ueno, Toshio ^a   Matsuda, Tamotsu ^b  

^a Asanogawa General Hospital   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

2 adrenoceptor; Cisplatin; Intraccllular accumulation; K+ ATPase; Lung cancer; Na+; Procaterol

Indexed keywords

3 (3,4 DIHYDROXYPHENYL) 2 [3 (4 FLUOROPHENYL)PROPYLAMINO] 3 HYDROXYPROPIONIC ACID PYRROLIDINE AMIDE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTINEOPLASTIC AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CATECHOL DERIVATIVE; CISPLATIN; DENOPAMINE; DRUG DERIVATIVE; ETHANOLAMINE DERIVATIVE; POTASSIUM; PROCATEROL; SERINE;

ARTICLE; CELL CULTURE; DRUG POTENTIATION; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; METABOLISM; PATHOLOGY;

ADRENERGIC BETA-AGONISTS; ANTINEOPLASTIC AGENTS; CARCINOMA, NON-SMALL-CELL LUNG; CATECHOLS; CISPLATIN; DRUG SYNERGISM; ETHANOLAMINES; HUMANS; LUNG NEOPLASMS; NA(+)-K(+)-EXCHANGING ATPASE; POTASSIUM; PROCATEROL; RECEPTORS, ADRENERGIC, BETA-2; SERINE; TUMOR CELLS, CULTURED;

EID: 0033630220     PISSN: 1021335X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Loehrer PJ and Einhorn LH: Cisplatin. Ann Intern Med 100: 704-713, 1984.
2. DeVita VT, Hellman S and Rodenberg SA: Cancer. Principles & Practice of Oncology. 4th edition. J.B. Lippincott Co., Philadelphia, pp673-758, 1993.
3. DeGraff A, Slebos RJC and Rodenhuis S: Resistance to cisplatin and analogues: mechanisms and potential clinical implications. Cancer Chemother Pharmacol 22: 325-332, 1988.
4. Hospers GAP, Mulder NH and DeVries EGE: Mechanisms of cellular resistance to cisplatin (review). Med Oncol Tumor Pharmacother 5: 145-151, 1988.
5. Kelley SL and Rosencweig M: Resistance to platinum compounds: mechanisms and beyond. Eur J Cancer Clin Oncol 25: 1135-1140, 1989.
6. Andrews PA and Howell SB: Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance. Cancer Cells 2: 35-43, 1990.
7. Andrews PA, Murphy MP and Howell SB: Metallothionein mediated cisplatin resistance in human ovarian carcinoma cells. Cancer Chemother Pharmacol 241: 1813-1815, 1987.
8. Tew KD, Bomber AM and Huffman SJ: Ethacrynic acid and piriprost as enhancer of cytotoxicity in drug resistant and sensitive cell lines. Cancer Res 48: 3622-3625, 1988.
9. Basu A and Lazo JS: A hypothesis regarding the prospective role of metallothionein against the toxicity of DNA intercalating drugs. Toxicol Lett 50: 123-125, 1990.
10. Fujiwara-Y, Sugimoto Y, Kasahara K, Bungo M, Yamakido M, Tew KD and Saijo N: Determinant of drug response in a cisplatin resistant human lung cancer cell line. Jpn J Cancer Res 81: 527-535, 1990.
11. Nakagawa K, Saijo N, Tsuchida S, Sakai M, Tsunokawa Y, Yokota J, Muramatsu M, Sato K, Terada M and Tew KD: Glutathione-S-transferase as a determinant of drug resistance in transfectant cell lines. J Biol Chem 265:4296-4301, 1990.
12. Kasahara K, Fujiwara Y, Nishio K, Ohmori T, Sugimoto Y, Komiya K, Matsuda T and Saijo N: Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin. Cancer Res 51: 3237-3242, 1991.
13. Eastman A and Schulte M: Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum (II). Biochemistry 27: 4730-4734, 1988.
14. Timmer-Bosscha Y, Mulder NH and DeVries EGE: Modulation of cis-diamminedichloroplatinum (II) resistance: a review. Br J Cancer 66: 227-238, 1992.
15. Gatery DP and Howell SB: Cellular accumulation of the anticancer agent cisplatin: a review. Br J Cancer 67: 1171-1176, 1993.
16. Bungo M, Fujiwara Y, Kasahara K, Nakagawa K, Ohe Y, Sasaki Y, Irino S and Saijo N: Decreased accumulation as a mechanisms of resistance to cis-diamminedichloroplatinum (II) in human non-small cell lung cancer cell lines: relation to DNA damage and repair. Cancer Res 50: 2549-2553, 1990.
17. Horisberger J-D, Lemas V, Kraehenbuhl J-P and Rossier BC: Structure-function relationship of Na, K-ATPase. Annu Rev Physiol 53: 565-584, 1991.
18. +-ATPase activity in airway relaxation induced by salbutamol. Life Sci 55: 217-223, 1994.