Chromogranin a expression in hepatocellular carcinoma in a patient with germline MEN1 gene mutation

Internal Medicine

Volumn 39, Issue 1, 2000, Pages 20-24

  Nakajima, Koji ^a   Sakurai, Akihiro ^a   Katai, Miyuki ^a   Yajima, Hiroki ^a   Mori, Jun Ichiro ^a   Katakura, Masafumi ^b   Tsuchiya, Shin Ichi ^c   Hashizume, Kiyoshi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b Koshoku Chuo Hospital   (Japan)

^c Nagano Cancer Detection Center   (Japan)

Author keywords

Glucagonoma; Multiple endocrine neoplasia type 1; Type C hepatitis

Indexed keywords

CHROMOGRANIN; CHROMOGRANIN A; CHROMOGRANIN A, HUMAN;

ARTICLE; CASE REPORT; CHEMISTRY; FATALITY; GENETICS; GLUCAGONOMA; HEPATITIS C; HUMAN; LIVER; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; MIDDLE AGED; MULTIPLE CANCER; MULTIPLE ENDOCRINE NEOPLASIA; MUTATION; PANCREAS; PANCREAS TUMOR;

CARCINOMA, HEPATOCELLULAR; CHROMOGRANIN A; CHROMOGRANINS; FATAL OUTCOME; GERM-LINE MUTATION; GLUCAGONOMA; HEPATITIS C; HUMANS; LIVER; LIVER NEOPLASMS; MALE; MIDDLE AGED; MULTIPLE ENDOCRINE NEOPLASIA TYPE 1; NEOPLASMS, MULTIPLE PRIMARY; PANCREAS; PANCREATIC NEOPLASMS;

EID: 0033627917     PISSN: 09182918     EISSN: None     Source Type: Journal    
DOI: 10.2169/internalmedicine.39.20     Document Type: Article

References (22)

1. Johnson RG Jr. Accumulation of biological amines into chromaffin granules: a model for hormone and neurotransmitter transport. Physiol Rev 68: 232-307, 1988.
2. Landsberg L. Chromogranin A. N Engl J Med 311: 794-795, 1984 (editorial).
3. O'Connor DT, Deftos LJ. Secretion of chromogranin A by peptide-producing endocrine neoplasms. N Engl J Med 314: 1145-1151, 1986.
4. Deftos LJ. Chromogranin A: Its role in endocrine function and as an endocrine and neuroendocrine tumor marker. Endocr Rev 12: 181-187, 1991.
5. Iacangelo A, Affolter H-U, Eiden LE, Herbert E, Grimes M. Bovine chromogranin A sequence and distribution of its messenger RNA in endocrine tissues. Nature 323: 82-86, 1986.
6. Hutton JC, Nielsen E, Kastern W. The molecular cloning of the chromogranin A-like precursor of β-granin and pancreastatin from the endocrine pancreas. FEBS Lett 236: 269-274, 1988.
7. Tatemoto K, Efendic S, Mutt V, Makk G, Feistner GJ, Barchas JD. Pancreastatin, a novel pancreatic peptide that inhibits insulin secretion. Nature 324: 476-478, 1986.
8. Nørgaard T, Bardram L. Endocrine liver tumour differential diagnosis from hepatocellular carcinoma. Histopathology 9: 777-781, 1985.
9. Tajima Y, Nakajima T, Sugano I, Nagao K, Kondo Y, Saito J. Hepatocellular carcinoma containing endocrine cells. An autopsy report of triplecancer involving the liver, kidney and thyroid. Acta Pathol Japon 42: 904-910, 1992.
10. Roskams T, Willems M, Campos RV, Drucker DJ, Yap SH, Desmet VJ. Parathyroid hormone-related peptide expression in primary and metastatic liver tumours. Histopathology 23: 519-525, 1993.
11. Chandrasekharappa SC, Guru SC, Manickam P, et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science 276: 404-407, 1997.
12. Sakurai A, Shirahama S, Fujimori M, et al. Novel MEN1 gene mutations in familial multiple endocrine neoplasia type 1. J Hum Genet 43: 199-201, 1998.
13. Edmondson HA. Tumors of the Liver and Intrahepatic Bile Duct. Armed Forces Institute of Pathology, Washington, 1958: 32-104.
14. Desmet VJ, Gerber M, Hoofnagle JH, Manns M, Scheuer PJ. Classification of chronic hepatitis: diagnosis, grading and staging. Hepatology 19: 1513-1520, 1994.
15. De Bruine AP, Wiggers T, Beek C, et al. Endocrine cells in colorectal adenocarcinomas: incidence, hormone profile and prognostic relevance. Int J Cancer 54: 765-771, 1995.
16. Ikeda Y, Mori M, Haraguchi Y, Sasaki O, Sugimachi K. The incidence of chromogranin A defined endocrine cells decreases with tumour progression in gastric adenocarcinoma. Surg Oncol 4: 255-260, 1995.
17. Wiedenmann B, Huttner WB. Synaptophysin and chromogranins/secretogranins: widespread constituents of distinct types of neuroendocrine vesicles and new toools in tumor diagnosis. Virchows Arch 58: 95-121, 1989.
18. Laforga JB, Lopez JI. Breast carcinoma with endocrine features. Report of a case with cytologic and immunohistochemical studies. Acta Cytol 42: 1017-1021, 1998.
19. Roskams T, De Vos R, van den Oord JJ, Desmet V. Cells with neuroendocrine features in regenerating human liver. APMIS Suppl 23: 32-39, 1991.
20. Pacchioni D, Papotti M, Macri L, Forte G, Bussolati G. Pancreatic oncocytic endocrine tumors. Cytologic features of two cases. Acta Cytol 40: 742-746, 1996.
21. Stewart C, Parente F, Piehl F, et al. Characterization of the mouse Men1 gene and its expression during development. Oncogene 17: 2485-2493, 1998.
22. Brandi ML, Marx SJ, Aurbach GD, Fitzpatrick LA. Familial multiple endocrine neoplasia type I: a new look at pathophysiology. Endocr Rev 8: 391-405, 1987.