αvβ3 and αvβ5 Integrin expression in meningiomas

Neurosurgery

Volumn 47, Issue 5, 2000, Pages 1185-1195

  Bello, Lorenzo ^a,b,d   Zhang, Jianping ^a   Nikas, Demetrios C ^a   Strasser, Jon F ^a   Villani, Roberto M ^b   Cheresh, David A ^c   Carroll, Rona S ^a   Black, Peter McL ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF MILAN   (Italy)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

^d CNR   (Italy)

Author keywords

Angiogenesis; Growth factors; Integrins; Meningiomas

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; INTEGRIN; VASCULOTROPIN; FIBROBLAST GROWTH FACTOR; MONOCLONAL ANTIBODY; VITRONECTIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; MENINGIOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR VASCULARIZATION; CELL CULTURE; CELL MOTION; EXTRACELLULAR MATRIX; METABOLISM; MIDDLE AGED; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

ADULT; AGED; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CELL MOVEMENT; ENDOTHELIUM, VASCULAR; EXTRACELLULAR MATRIX; FEMALE; FIBROBLAST GROWTH FACTORS; HUMANS; IMMUNOHISTOCHEMISTRY; INTEGRINS; MALE; MENINGEAL NEOPLASMS; MENINGIOMA; MIDDLE AGED; NEOVASCULARIZATION, PATHOLOGIC; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; VITRONECTIN;

EID: 0033626430     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00006123-200011000-00035     Document Type: Article

References (42)

1. Biological roles of fibroblast growth factor- 2
2. Meningiomas
3. Platelet-derived growth factor expression and stimulation in human meningiomas
4. The molecular biology of hormone and growth factor receptors in meningiomas
5. Immunolocalization of basic fibroblast growth factor to the microvasculature of human brain tumors
6. Role of integrins in angiogenesis
7. Requirement of vascular integrin alpha v beta 3 for angiogenesis
8. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
9. Anti-integrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin
10. Expression and activation of epidermal growth factor receptor in meningiomas
11. Progesterone receptor in meningiomas
12. Progesterone and glucocorticoid receptor activation in meningiomas
13. Androgen receptor expression in meningiomas
14. Biosynthetic and functional properties of an Arg-Gly-Asp-directed receptor involved in human melanoma cell attachment to vitronectin and von Willebrand factor
15. Immunohistochemical detection of vascular growth factors in angiomatous and atypical meningiomas, as well as hemangiopericytomas
16. Cell-adhesion molecules in human meningiomas: Correlation with clinical and morphological data
17. Definition of two angiogenic pathways by distinct alpha v integrins
18. Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves αV and β 1 integrins
19. The alpha v beta 3 integrin 'vitronectin receptor'
20. Integrins: Versatility, modulation and signaling in cell adhesion
21. Correlation of vascular endothelial growth factor messenger RNA expression with peritumoral vasogenic cerebral edema in meningiomas
22. Receptor tyrosine kinase signaling required for integrin alphavbeta5-directed cell motility but not adhesion on vitronectin
23. Pathology of meningiomas
24. The biology of meningiomas
25. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function
26. Integrins can collaborate with growth factor for phosphorylation of receptor tyrosine kinase and MAP kinase activation: Role of integrin aggregation and occupation of receptors
27. Characterization of integrin receptors in normal and neoplastic human brain
28. Expression and distribution of vascular endothelial growth factor protein in human brain tumors
29. Alpha 6 beta4 and alpha6 beta1 integrins in astrocytomas and other CNS tumors
30. Meningiomas: Role of vascular endothelial growth factor/ vascular permeability factor in angiogenesis and peritumoral edema
31. Integrins
32. Alphavbeta3 integrin mediates the cell-adhesive capacity and biological activity of basic fibroblast growth factor (FGF-2) in cultured endothelial cells
33. Expression of vascular endothelial growth factor and its possible relation with neovascularization in human brain tumors
34. Alphavbeta 3 integrin associates with activated insulin and PDGFbeta receptors and potentiates the biological activity of PDGF
35. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin and thrombin
36. Detection of activated platelet derived growth factor receptors in human meningiomas
37. The αvβ3 integrin regulates α5β1-mediated cell migration toward fibronectin
38. Endothelial cell attachment on human tenascin is mediated by alpha 2beta1 and alphavbeta3 integrins
39. Tumor angiogenesis and the role of vascular cell integrin alphavbeta 3
40. Expression of adhesion molecules and extracellular matrix proteins in glioblastomas: Relation to angiogenesis and spread
41. Integrins alpha v beta 3 and alpha v beta 5 contribute to cell attachment to vitronectin but differentially distribute on the cell surface
42. Tumor angiogenesis and metastasis: Correlation in invasive breast carcinoma