Comparison of the Ca2+ entry channels responsible for mechanical responses of guinea-pig aorta to noradrenaline and thapsigargin using SK and F 96365 and LOE 908

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 362, Issue 2, 2000, Pages 160-168

  Tanaka, Y ^a   Imai, T ^a   Igarashi, T ^a   Takayanagi, K ^a   Otsuka, K ^a   Yamaki, F ^a   Tanaka, H ^a   Shigenobu, K ^a  

^a TOHO UNIVERSITY   (Japan)

Author keywords

Guinea pig aorta; LOE 908; Noradrenaline induced contraction; SK and F 96365; Store operated Ca2+ channel; Thapsigargin

Indexed keywords

(3,4 DIHYDRO 6,7 DIMETHOXY ISOQUINOLINE 1 YL) 2 PHENYL N,N DI [2 (2,3,4 TRIMETHOXYPHENYL)ETHYL] ACETAMIDE; (3,4 DIHYDRO 6,7 DIMETHOXYISOQUINOLINE 1 YL) 2 PHENYL N,N DI [2 (2,3,4 TRIMETHOXYPHENYL)ETHYL]ACETAMIDE; 1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 1 [[6 (3 METHOXYESTRA 1,3,5(10) TRIEN 17BETA YL)AMINO]HEXYL] 1H PYRROLE 2,5 DIONE; ADENOSINE TRIPHOSPHATASE (CALCIUM); CALCIUM CHANNEL; CALCIUM ION; CINNAMIC ACID DERIVATIVE; DILTIAZEM; DIPHENYLCARBAMIC ACID 4 CARBOXY 2 NITROPHENYL ESTER; FURA 2 ACETOXYMETHYL ESTER; NICARDIPINE; NORADRENALIN; PROSTAGLANDIN F2 ALPHA; TETRODOTOXIN; THAPSIGARGIN; UNCLASSIFIED DRUG; VERAPAMIL; 1 (2 (3 (4 METHOXYPHENYL)PROPOXY) 4 METHOXYPHENYLETHYL) 1H IMIDAZOLE; 1-(2-(3-(4-METHOXYPHENYL)PROPOXY)-4-METHOXYPHENYLETHYL)-1H-IMIDAZOLE; 2 (3,4 DIHYDRO 6,7 DIMETHOXY 1 ISOQUINOLINYL) 2 PHENYL N,N BIS[2 (2,3,4 TRIMETHOXYPHENYL)ETHYL]ACETAMIDE; ACETAMIDE DERIVATIVE; CALCIUM CHANNEL BLOCKING AGENT; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; ISOQUINOLINE DERIVATIVE; PHOSPHOLIPASE C;

ANIMAL TISSUE; AORTA; ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE; CONTROLLED STUDY; CYTOPLASM; ENDOTHELIUM CELL; FEMALE; GUINEA PIG; ISOLATED ARTERY; MALE; MUSCLE TONE; NONHUMAN; VASOCONSTRICTION; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; EXTRACELLULAR SPACE; IN VITRO STUDY; METABOLISM; MUSCLE CONTRACTION; MUSCLE RELAXATION; THORACIC AORTA; VASCULAR SMOOTH MUSCLE;

ACETAMIDES; ANIMALS; AORTA, THORACIC; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CELL MEMBRANE; CYTOPLASM; ENZYME INHIBITORS; EXTRACELLULAR SPACE; FEMALE; GUINEA PIGS; IMIDAZOLES; ISOQUINOLINES; MALE; MUSCLE CONTRACTION; MUSCLE RELAXATION; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; PHOSPHOLIPASE C; THAPSIGARGIN;

EID: 0033626305     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100000272     Document Type: Article

References (23)

1. 2+ signaling requirements
2. 2+ entry pathway in human endothelial cells by the isoquinoline derivative LOE 908
3. 2+ entry and the regulation of smooth muscle tone
4. Actions of nifedipine on calcium fluxes and contraction in isolated rat arteries
5. 2+ entry blockers contributes to noradrenaline-induced contractions of the isolated guinea pig aorta
6. 2+ entry for endothelial nitric oxide production
7. 1-adrenoceptors
8. Calcium movements, distribution, and functions in smooth muscle
9. Mechanism of contraction to endothelin in isolated porcine coronary artery
10. Endothelin-1 induces vasoconstriction through two functionally distinct pathways in porcine coronary artery: Contribution of phosphoinositide turnover
11. The isoquinoline derivative LOE 908 selectively blocks vasopressin-activated nonselective cation currents in A7r5 aortic smooth muscle cells
12. SK and F 96365, a novel inhibitor of receptor-mediated calcium entry
13. 2+ channels and phospholipase C
14. 2+ levels and muscle contraction in isolated guinea pig aorta
15. 2+ entry?
16. Differential sensitivity to ATP-sensitive potassium channel openers of norepinephrine-induced contraction of guinea pig and rat aorta
17. Effects of endothelin on the mechanical activity and cytosolic calcium level of various types of smooth muscle
18. Changes in cytosolic calcium level in vascular smooth muscle strip measured simultaneously with contraction using fluorescent calcium indicator fura 2
19. Comparison of contractions produced by carbachol, thapsigargin and cyclopiazonic acid in the guinea-pig tracheal muscle
20. 2+ concentration changes by use of fura-2 in the generation of myogenic contraction of dog cerebral artery in response to quick stretch
21. 2+ entry and its pharmacological characteristics responsible for endothelium-dependent, NO-mediated relaxation induced by thapsigargin in guinea-pig aorta
22. 2+ ionophore, A23187
23. 2+ entry channels in endothelin-1-induced contraction of rat aorta using LOE 908 and SK and F 96365