[123I]IPCIT and [123I]β-CIT as SPECT tracers for the dopamine transporter: A comparative analysis in nonhuman primates

Nuclear Medicine and Biology

Volumn 27, Issue 1, 2000, Pages 13-21

  Scanley, B E ^a   Gandelman, M S ^b   Laruelle, M ^c   Al Tikriti, M S ^a   Baldwin, R M ^a   Zoghbi, S S ^a   Hoffer, P B ^a   Wang, S ^d   Neumeyer, J L ^e   Innis, R B ^a  

^a VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^b PFIZER INC   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

^d Research Biochemicals International   (United States)

^e HARVARD MEDICAL SCHOOL   (United States)

Author keywords

CIT; Compartmental modeling; Dopamine transporter; IPCIT; SPECT

Indexed keywords

COCAINE DERIVATIVE; DOPAMINE TRANSPORTER; IODINE 123; TROPANE DERIVATIVE; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID ISOPROPYL ESTER; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; CARRIER PROTEIN; COCAINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; LIGAND; MEMBRANE PROTEIN; NERVE PROTEIN; RADIOACTIVE IODINE;

ARTICLE; BABOON; CORPUS STRIATUM; MODEL; OCCIPITAL CORTEX; PRIMATE; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; TISSUE DISTRIBUTION; ANIMAL; BIOLOGICAL MODEL; BLOOD; BRAIN; COMPARATIVE STUDY; FEMALE; HALF LIFE TIME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; METABOLIC CLEARANCE RATE; METABOLISM; PAPIO; SCINTISCANNING; SPECIES DIFFERENCE; TIME;

ANIMALS; BRAIN; CARRIER PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; FEMALE; HALF-LIFE; HUMANS; INJECTIONS, INTRAVENOUS; IODINE RADIOISOTOPES; LIGANDS; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; METABOLIC CLEARANCE RATE; MODELS, BIOLOGICAL; NERVE TISSUE PROTEINS; PAPIO; SPECIES SPECIFICITY; TIME FACTORS; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0033625013     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0969-8051(99)00083-9     Document Type: Article

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