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Volumn , Issue 59, 2000, Pages 155-161

Genetics of Alzheimer's disease - Routes to the pathophysiology

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOLIPOPROTEIN E; PRESENILIN 1; PRESENILIN 2; ISOPROTEIN; MEMBRANE PROTEIN; PSEN1 PROTEIN, HUMAN; PSEN2 PROTEIN, HUMAN;

EID: 0033624414     PISSN: 03036995     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-7091-6781-6_17     Document Type: Review
Times cited : (5)

References (27)
  • 1
    • 0027988641 scopus 로고
    • A large Swedish family with Alzheimer's disease with a codon 670/671 amyloid precursor protein mutation: A clinical and genealogical investigation
    • Axelman K, Basun H, Winblad B, Lannfelt L (1994) A large Swedish family with Alzheimer's disease with a codon 670/671 amyloid precursor protein mutation: A clinical and genealogical investigation. Arch Neurol 51: 1193-1197
    • (1994) Arch Neurol , vol.51 , pp. 1193-1197
    • Axelman, K.1    Basun, H.2    Winblad, B.3    Lannfelt, L.4
  • 2
    • 0027526419 scopus 로고
    • Release of excess amyloid β protein from a mutant amyloid β protein precursor
    • Cai XD, Golde TE, Younkin SG (1993) Release of excess amyloid β protein from a mutant amyloid β protein precursor. Science 259: 514-516
    • (1993) Science , vol.259 , pp. 514-516
    • Cai, X.D.1    Golde, T.E.2    Younkin, S.G.3
  • 3
    • 0026745610 scopus 로고
    • Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
    • Citron M, Oltersdorf T, Haass C, McConlogue L, Hung AY, Seubert P et al (1992) Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production. Nature 360: 672-674
    • (1992) Nature , vol.360 , pp. 672-674
    • Citron, M.1    Oltersdorf, T.2    Haass, C.3    McConlogue, L.4    Hung, A.Y.5    Seubert, P.6
  • 5
    • 0029803744 scopus 로고    scopus 로고
    • Evidence that the 42-and 40-amino acid forms of amyloid β protein are generated from the β-amyloid precursor protein by different protease activities
    • Citron M, Diehl TS, Gordon G, Biere AL, PS, Selkoe DJ (1996) Evidence that the 42-and 40-amino acid forms of amyloid β protein are generated from the β-amyloid precursor protein by different protease activities. Proc Natl Acad Sci USA 93: 13170-13175
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 13170-13175
    • Citron, M.1    Diehl, T.S.2    Gordon, G.3    Biere, A.L.4    P, S.5    Selkoe, D.J.6
  • 6
    • 0029813255 scopus 로고    scopus 로고
    • The presenilin genes: A new gene family involved in Alzheimer disease pathology
    • Cruts M, Hendriks L, Van Broeckhoven C (1996) The presenilin genes: a new gene family involved in Alzheimer disease pathology. Hum Mol Genet 5: 1449-1455
    • (1996) Hum Mol Genet , vol.5 , pp. 1449-1455
    • Cruts, M.1    Hendriks, L.2    Van Broeckhoven, C.3
  • 7
    • 0028972701 scopus 로고
    • Image analysis of β-amyloid load in Alzheimer's disease and relation to dementia
    • Cummings BJ, Cotman CW (1995) Image analysis of β-amyloid load in Alzheimer's disease and relation to dementia. Lancet 346: 1524-1527
    • (1995) Lancet , vol.346 , pp. 1524-1527
    • Cummings, B.J.1    Cotman, C.W.2
  • 8
    • 0028201821 scopus 로고
    • APP processing, Aβ amyloidogenesis, and the pathogenesis of Alzheimer's disease
    • Gandy S, Caporaso G, Buxbaum J, Frangione B, Greengard P (1994) APP processing, Aβ amyloidogenesis, and the pathogenesis of Alzheimer's disease. Neurobiol Aging 15: 253-256
    • (1994) Neurobiol Aging , vol.15 , pp. 253-256
    • Gandy, S.1    Caporaso, G.2    Buxbaum, J.3    Frangione, B.4    Greengard, P.5
  • 9
    • 0021207461 scopus 로고
    • Alzheimer's disease and Down's syndrome: Sharing of a unique cerebrovascular amyloid fibril protein
    • Glenner GG, Wong CW (1984) Alzheimer's disease and Down's syndrome: sharing of a unique cerebrovascular amyloid fibril protein. Biochem Biophys Res Commun 122: 1131-1135
    • (1984) Biochem Biophys Res Commun , vol.122 , pp. 1131-1135
    • Glenner, G.G.1    Wong, C.W.2
  • 10
    • 0026088977 scopus 로고
    • Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
    • Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L et al (1991) Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature 349: 704-706
    • (1991) Nature , vol.349 , pp. 704-706
    • Goate, A.1    Chartier-Harlin, M.C.2    Mullan, M.3    Brown, J.4    Crawford, F.5    Fidani, L.6
  • 11
    • 0027195933 scopus 로고
    • Seeding "one-dimensional crystallization" of amyloid. A pathogenic mechanism in Alzheimer's disease and scrapie?
    • Jarret JT, Lansbury PT (1993) Seeding "one-dimensional crystallization" of amyloid. A pathogenic mechanism in Alzheimer's disease and scrapie? Cell 73: 1055-1058
    • (1993) Cell , vol.73 , pp. 1055-1058
    • Jarret, J.T.1    Lansbury, P.T.2
  • 12
    • 0028171524 scopus 로고
    • Increased β-amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutation
    • Johnston J, Cowburn RF, Norgren S, Wiehager B, Venizelos N, Winblad B, Vigo-Pelfrey C, Schenk D, Lannfelt L, O'Neill C (1994) Increased β-amyloid release and levels of amyloid precursor protein (APP) in fibroblast cell lines from family members with the Swedish Alzheimer's disease APP670/671 mutation. FEBS Lett 354: 274-278
    • (1994) FEBS Lett , vol.354 , pp. 274-278
    • Johnston, J.1    Cowburn, R.F.2    Norgren, S.3    Wiehager, B.4    Venizelos, N.5    Winblad, B.6    Vigo-Pelfrey, C.7    Schenk, D.8    Lannfelt, L.9    O'Neill, C.10
  • 13
    • 0023105114 scopus 로고
    • The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
    • Kang J, Lemaire H-G, Unterbeck A, Salbaum JM, Masters CL, Grzeschik K-H et al (1987) The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature 325: 733-736
    • (1987) Nature , vol.325 , pp. 733-736
    • Kang, J.1    Lemaire, H.-G.2    Unterbeck, A.3    Salbaum, J.M.4    Masters, C.L.5    Grzeschik, K.-H.6
  • 16
    • 0026907151 scopus 로고
    • A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid
    • Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, Winblad B, Lannfelt L (1992) A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of β-amyloid. Nat Genet 1: 345-347
    • (1992) Nat Genet , vol.1 , pp. 345-347
    • Mullan, M.1    Crawford, F.2    Axelman, K.3    Houlden, H.4    Lilius, L.5    Winblad, B.6    Lannfelt, L.7
  • 18
    • 0014481635 scopus 로고
    • Presenil dementia and Alzheimer's disease in mongolism
    • Olson M, Shaw C (1969) Presenil dementia and Alzheimer's disease in mongolism. Brain 92: 147-156
    • (1969) Brain , vol.92 , pp. 147-156
    • Olson, M.1    Shaw, C.2
  • 20
    • 0029101491 scopus 로고
    • Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene
    • Rogaev EI, Sherrington R, Rogaeva EA, Levesque G, Ikeda M, Liang Y et al (1995) Familial Alzheimer's disease in kindreds with missense mutations in a gene on chromosome 1 related to the Alzheimer's disease type 3 gene. Nature 376: 775-778
    • (1995) Nature , vol.376 , pp. 775-778
    • Rogaev, E.I.1    Sherrington, R.2    Rogaeva, E.A.3    Levesque, G.4    Ikeda, M.5    Liang, Y.6
  • 21
  • 23
    • 0027367764 scopus 로고
    • Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease
    • Selkoe DJ (1993) Physiological production of the β-amyloid protein and the mechanism of Alzheimer's disease. Trends Neurol Sci 16: 403-409
    • (1993) Trends Neurol Sci , vol.16 , pp. 403-409
    • Selkoe, D.J.1
  • 24
    • 0031038918 scopus 로고    scopus 로고
    • Alzheimer's disease: Genotypes, phenotype, and treatments
    • Selkoe DJ (1997) Alzheimer's disease: genotypes, phenotype, and treatments. Science 275: 630-631
    • (1997) Science , vol.275 , pp. 630-631
    • Selkoe, D.J.1
  • 25
    • 0029004341 scopus 로고
    • Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
    • Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M et al (1995) Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375: 754-760
    • (1995) Nature , vol.375 , pp. 754-760
    • Sherrington, R.1    Rogaev, E.I.2    Liang, Y.3    Rogaeva, E.A.4    Levesque, G.5    Ikeda, M.6
  • 26
    • 0002479711 scopus 로고
    • Morbus Alzheimer and Morbus Pick. A genetic, clinical and patho-anatomical study
    • Sjögren T, Sjögren H, Lindgren ÅG (1952) Morbus Alzheimer and Morbus Pick. A genetic, clinical and patho-anatomical study. Acta Psychiatr Scand Suppl 82
    • (1952) Acta Psychiatr Scand Suppl , vol.82
    • Sjögren, T.1    Sjögren, H.2    Lindgren, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.