The polyneuropathy associated with Waldenstrom's macroglobulinaemia can be treated effectively with chemotherapy and the anti-CD20 monoclonal antibody rituximab

British Journal of Haematology

Volumn 109, Issue 4, 2000, Pages 838-841

  Weide, R ^a   Heymanns, J ^a   Koppler H ^a  

^a Haematology/Oncology Group Practice   (Germany)

Author keywords

Polyneuropathy; Rituximab; Waldenstrom's macroglobulinaemia

Indexed keywords

CHLORAMBUCIL; MITOXANTRONE; PREDNISONE; RITUXIMAB; ANTINEOPLASTIC AGENT; MONOCLONAL ANTIBODY;

ADULT; ARTICLE; CANCER IMMUNOTHERAPY; CASE REPORT; DISEASE ASSOCIATION; DRUG EFFICACY; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; POLYNEUROPATHY; PRIORITY JOURNAL; TREATMENT OUTCOME; WALDENSTROEM MACROGLOBULINEMIA; MIDDLE AGED;

ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; HUMANS; MALE; MIDDLE AGED; POLYNEUROPATHIES; WALDENSTROM MACROGLOBULINEMIA;

EID: 0033624240     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2000.02086.x     Document Type: Article

References (12)

1. Baumann, I., Krause, T., Schwenke, H. & Lehmann, J. (1990) Experiences in the diagnosis and treatment of polyneuropathies in patients with malignant monoclonal gammopathy. Psychiatrics Neurological Medicine Psychological (Leipzig), 42, 85-95.
2. Bosch, P. & Smith, B.E. (1993) Peripheral neuropathies associated with monoclonal proteins. Medicine Clinical North America, 77, 125-139.
3. Byrd, J.C., White, C.A., Link, B., Thomas, S., Valasquez, W.S., Rosenberg, J. & Grillo-Lopez, A.J. (1998) rituximab therapy in previously treated Waldenström's macroglobulinemia. Blood, 92, 433a (Abstract Suppl. 1).
4. Dimopoulos, M.A. & Alexanian, R. (1994) Waldenström's macroglobulinemia. Blood, 83, 1452-1459.
5. Gordon, P.H., Rowland, L.P., Younger, D.S., Sherman, W.H., Hays, A.P., Louis, E.D., Lange, D.J., Trojaborg, W., Lovelace, R.E., Murphy, P.L. & Latov, N. (1997) Lymphoproliferative disorders and motor neuron disease: an update. Neurology, 48, 1671-1678.
6. Hoppe, U., Drager, H.S., Patzold, U., Stark, E., Wurster, U. & Deicher, H. (1987) Polyneuropathy in Waldenstrom's macroglobulinaemia. Passive transfer from man to mouse. Acta Neurological Scandinavian, 75, 112-116.
7. Kelly, J.J., Adelman, L.S., Berkman, E. & Bhan, I. (1988) Polyneuropathies associated with IgM monoclonal gammopathies. Archives of Neurology, 45, 1355-1359.
8. McLaughlin, P., Cabanillas, F., Grillo-Lopez, A.J., Link, B.K., Levy, R., Czuczman, M., Heyman, M.R., Williams, M., Jain, V., Bence-Bruckler, I., Ho, A.D., Lister, J., Rosenberg, J., Dallaire, B.K. & Shen, D. (1996) IDEC-C2B8 anti-CD20 antibody: final report on a phase III pivotal trial in patients with relapsed low grade or follicular lymphoma. Blood, 88, 90a (Abstract Suppl. 1).
9. Monaco, S., Bonetti, B., Ferrari, S., Moretto, G., Nardelli, E., Tedesco, F., Mollnes, T.E., Nobile-Orazio, E., Manfedini, E. & Bonazzi, L. (1990) Complement-mediated demyelination in patients with IgM monoclonal gammopathy and polyneuropathy. New England Journal of Medicine, 322, 649-652.
10. Pavord, S.R., Murphy, P.T. & Mitchell, V.E. (1996) POEMS syndrome and Waldenström's macroglobulinaemia. Journal of Clinical Pathology, 49, 181-182.
11. Vrethem, M., Cruz, M., Wen-Xin, H., Malm, C., Holmgren, H. & Ernerudh, J. (1993) Clinical, neurophysiological and immunological evidence of polyneuropathy in patients with monoclonal gammopathies. Journal of Neurological Science, 114, 193-199.
12. Weide, R., Heymanns, J. & Köppler, H. (1999) Induction of complete haematological remission after monotherapy with anti-CD20 monoclonal antibody (rituximab) in a patient with alkylating agent resistant Waldenström's Macroglobulinaemia. Leukemia and Lymphoma, 36, 203-206.