Amifostine, a reactive oxygen species scavenger with radiation- and chemo-protective properties, inhibits in vitro platelet activation induced by ADP, collagen or PAF

Haematologica

Volumn 85, Issue 8, 2000, Pages 820-825

  Porta, C ^a   Maiolo, A ^a   Tua, A ^a   Grignani, G ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

Amifostine; Nitric oxide; Platelet function; Reactive oxygen species

Indexed keywords

ADENOSINE DIPHOSPHATE; AMIFOSTINE; COLLAGEN; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; SCAVENGER; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE B2; ANTIOXIDANT; ANTITHROMBOCYTIC AGENT; RADIOPROTECTIVE AGENT;

ADULT; ARTICLE; CELL PROTECTION; COLORIMETRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NORMAL HUMAN; RADIOIMMUNOASSAY; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION INHIBITION; BIOSYNTHESIS; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; OXIDATIVE STRESS; THROMBOCYTE;

ADENOSINE DIPHOSPHATE; ADULT; AMIFOSTINE; ANTIOXIDANTS; BLOOD PLATELETS; COLLAGEN; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; HUMANS; NITRIC OXIDE; OXIDATIVE STRESS; PLATELET ACTIVATING FACTOR; PLATELET ACTIVATION; PLATELET AGGREGATION INHIBITORS; RADIATION-PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES; THROMBOXANE B2;

EID: 0033624152     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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