Activating transcripton factor-2 is a positive regulator in CaM kinase IV-induced human insulin gene expression

Diabetes

Volumn 49, Issue 7, 2000, Pages 1142-1148

  Ban, Nobuhiro ^a   Yamada, Yuichiro ^a   Someya, Yoshimichi ^a   Ihara, Yu ^a   Adachi, Tetsuya ^a   Kubota, Akira ^a   Watanabe, Rie ^a   Kuroe, Akira ^a   Inada, Akari ^a   Miyawaki, Kazumasa ^a   Sunaga, Yasuhiro ^a   Shen, Zhen Ping ^a   Iwakura, Toshio ^a   Tsukiyama, Katsushi ^a   Toyokuni, Shinya ^a   Tsuda, Kinsuke ^a   Seino, Yutaka ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; INSULIN; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; THREONINE; TRANSCRIPTION FACTOR; ACTIVATING TRANSCRIPTION FACTOR 2; ATF2 PROTEIN, HUMAN; ATF2 PROTEIN, MOUSE; ATF2 PROTEIN, RAT; CALMODULIN DEPENDENT PROTEIN KINASE IV; CALMODULIN-DEPENDENT PROTEIN KINASE IV; GLUCOSE; LUCIFERASE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; GENE REPRESSION; GENETIC TRANSCRIPTION; GLUCOSE HOMEOSTASIS; INSULIN SYNTHESIS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; RAT; AMINO ACID SUBSTITUTION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECT; GENETIC TRANSFECTION; GENETICS; HAMSTER; HUMAN; MALE; METABOLISM; MOUSE; PANCREAS ISLET; SITE DIRECTED MUTAGENESIS; TRANSACTIVATION; WISTAR RAT;

ACTIVATING TRANSCRIPTION FACTOR 2; AMINO ACID SUBSTITUTION; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL LINE; CRICETINAE; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INSULIN; ISLETS OF LANGERHANS; LUCIFERASES; MALE; MICE; MUTAGENESIS, SITE-DIRECTED; PROMOTER REGIONS (GENETICS); RATS; RATS, WISTAR; RECOMBINANT PROTEINS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0033624125     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.49.7.1142     Document Type: Article

References (26)

1. Gonzalez GA, Montminy MR: Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell 59:675-680, 1989
2. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH: Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855-859, 1993
3. Kwok RP, Lundblad JR, Chrivia JC, Richards JP, Bachinger HP, Brennan RG, Roberts SG, Green MR, Goodman RH: Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370:223-226, 1994
4. 2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev 8:2527-2539, 1994
5. Lundblad JR, Kwok RP, Laurance ME, Harter ML, Goodman RH: Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP. Nature 374:85-88, 1995
6. Maekawa T, Sakura H, Kanei Ishii C, Sudo T, Yoshimura T, Fujisawa J, Yoshida M, Ishii S: Leucine zipper structure of the protein CRE-BP1 binding to the cyclic AMP response element in brain. EMBO J 8:2023-2028, 1989
7. Hai TW, Liu F, Coukos WJ, Green MR: Transcription factor ATF cDNA clones: an extensive family of leucine zipper proteins able to selectively form DNA-binding heterodimers. Genes Dev 3:2083-2090, 1989
8. Montminy M: Transcriptional regulation by cyclic AMP. Annu Rev Biochem 66:807-822, 1997
9. Inagaki N, Maekawa T, Sudo T, Ishii S, Seino Y, Imura H: c-Jun represses the human insulin promoter activity that depends on multiple cAMP response elements. Proc Natl Acad Sci U S A 89:1045-1049, 1992
10. Gupta S, Campbell D, Derijard B, Davis RI: Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267:389-393, 1995
11. Gorman CM, Moffat LF, Howard BH: Rocombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol 2:1044-1051, 1982
12. Ihara Y, Toyokuni S, Uchida K, Okada K, Tanaka T, Ikada H, Hiai H, Seino Y, Yamada Y: Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. Diabetes 48:927-932, 1999
13. Hsu SM, Raine L, Fanger H: A comparative study of the peroxidase-antiperoxidase method and an avidin-biotin complex method for studying polypeptide hormones with radioimmunoassay antibodies. Am J Clin Pathol 75:734-738, 1981
14. Sutton R, Peters M, McShane P, Gray DW, Morris PJ: Isolation of rat pancreatic islets by ductal injection of collagenase. Transplantation 42:689-691, 1986
15. + channels in pancreatic β-cells in streptozotocin-induced NIDDM rats. Diabetes 41:861-865, 1992
16. 2+ and stimulus duration-dependent switch for hippocampal gene expression. Cell 87:1203-1214, 1996
17. 2+/calmodulin-dependent protein kinase, CaM kinase-Gr, in rat thymus. J Biol Chem 266:17592-17596, 1991
18. Flint KJ, Jones NC: Differential regulation of three members of the ATF/CEEB family of DNA-binding proteins. Oncogene 6:2019-2026, 1991
19. Santella L, Carafoli E: Calcium signaling in the cell nucleus. FASEB J 11:1091-1109, 1997
20. Deisseroth K, Heist EK, Tsien RW: Translocation of calmodulin to the nucleus supports CREB phosphorylation in hippocampal neurons. Nature 392:198-202, 1998
21. 2-terminal kinase isoform and induction of neunte outgrowth in PC-12 cells by staurosporine. J Biol Chem 272:18261-18266, 1997
22. Enslen H, Tokumitsu H, Stork PJ, Davis RJ, Soderling TR: Regulation of mitogen-activated protein kinases by a calcium/calmodulin-dependent protein kinase cascade. Proc Natl Acad Sci U S A 93:10803-10808, 1996
23. Charles MA, Lawecki J, Pictet R, Grodsky GM: Insulin secretion: interrelationships of glucose, cyclic adenosine 3:5-monophosphate, and calcium. J Biol Chem 250:6134-6140, 1975
24. Wollheim CB, Sharp GW: Regulation of insulin release by calcium. Physiol Rev 61:914-973, 1981
25. Oetjen E, Diedrich T, Eggers A, Eckert B, Knepel W: Distinct properties of the cAMP-responsive element of the rat insulin I gene. J Biol Chem 269:27036-27044, 1994
26. Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin SC, Heyman RA, Rose DW, Glass CK, Rosenfeld MG: A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85: 403-414, 1996