T3 directly stimulates basal and modulates LH induced testosterone and oestradiol production by rat Leydig cells in vitro

Endocrine Journal

Volumn 47, Issue 4, 2000, Pages 417-428

  Maran, R R M ^a   Arunakaran, J ^a   Aruldhas, M M ^a  

^a MCGILL UNIVERSITY   (Canada)

Author keywords

Leydig cells; LH; Oestradiol; T3; Testosterone

Indexed keywords

ANDROSTENEDIONE; ESTRADIOL; LIOTHYRONINE; LUTEINIZING HORMONE; PUROMYCIN; TESTOSTERONE;

ADOLESCENT; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ESTROGEN RELEASE; ESTROGEN SYNTHESIS; IN VITRO STUDY; LEYDIG CELL; MALE; NONHUMAN; PUBERTY; RADIOIMMUNOASSAY; RAT; TESTOSTERONE RELEASE; TESTOSTERONE SYNTHESIS; ANIMAL; DRUG EFFECT; DRUG INTERACTION; METABOLISM; SECRETION; WISTAR RAT;

ANDROSTENEDIONE; ANIMALS; DRUG INTERACTIONS; ESTRADIOL; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; PUROMYCIN; RATS; RATS, WISTAR; TESTOSTERONE; TRIIODOTHYRONINE;

EID: 0033623506     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.47.417     Document Type: Article

References (46)

1. 1 mRNA expression in the rat testis
2. Variant thyroid hormone receptor (THR) isoforms in developing rat testis
3. Thyroid hormone and male gonadal function
4. Influence of hypothyroidism on in vitro testicular steroidogenesis in adult rats
5. Effect of thyroidectomy, and thyroxine and α(2μ)-globulin replacement therapy on testicular steroidogenic and gametogenic activities in rats
6. Inhibition of Leydig cell activity in vivo and in vitro in hypothyroid rats
7. Leydig cells increase their numbers but decline in steroidogenic function in the adult rat after neonatal hypothyroidism
8. Transient neonatal hypothyroidism alters plasma and testicular sex steroids concentration in puberal rats
9. Nuclear triiodothyronine receptors in rat Sertoli cells
10. 2 and β and native 3,5,3'-triiodothyronine receptor, and study of tissue distribution of the antigen
11. 3 receptor
12. Binding of thyroid hormone to the goat Leydig cell induces the generation of a proteinaceous factor which stimulates androgen release
13. Thyroid hormones induce a 52 kDa soluble protein in goat testis Leydig cell which stimulates androgen release
14. Increased proliferation of Leydig cells induced by neonatal hypothyroidism in the rat
15. Decreased steroidogenesis and cAMP production in vitro by Leydig cells isolated from rats made hypothyroid during adulthood
16. Age related changes in gonadotropin receptors in testes of rats
17. Sertoli and Leydig cell numbers and gonadotropin receptors in rat testis from birth to puberty
18. Multichamber cell culture and directional secretion
19. hCG responsiveness of purified Leydig cells from immature and mature rats
20. The effect of cell damage on the density and the steroidogenic capacity of rat testis Leydig cells. Using an NADH exclusion test for determination of viability
21. 1 in the control of steroidogenesis in cultured porcine Leydig cells
22. Effect of puromycin and actinomycin D on glucose-stimulated protein and RNA labeling in vitro, in rat testis
23. Testosterone and oestradiol assays
24. Thyroid hormone stimulates the production of insulin-like growth factor I (IGF-I) by rat Sertoli cells
25. Hormonal regulation of androgen production by the Leydig cell
26. Endocrine regulation and communicating functions of the Leydig cell
27. Hormonal control mechanisms of Leydig cells
28. Fetal Leydig cells: Cellular origin, morphology, life span and special functional features
29. Transcriptional and translational regulation of LH, prolactin and their testicular receptors by hCG and bromocriptine treatments in adult and neonatal rats
30. Functional maturation of rat testis Leydig cells
31. Hormonal regulation of gonadotropin receptors and steroidogenesis in cultured fetal rat testes
32. Cellular localization of rat testicular aromatase activity during development
33. Gonadotropic regulation of aromatase activity in the adult rat testis
34. Steroid production, metabolism and release by Sertoli cells
35. Estradiol receptor-mediated regulation of steroidogenesis in gonadotropin-desensitized Leydig cells
36. Effects of hCG and cyclic AMP on aromatization in purified Leydig cells of immature and mature rats
37. Gondadotropin-induced desensitization of Leydig cells in vivo and in vitro estrogen actgion in the testis
38. Impact of altered thyroid hormone status on prostatic glycosidases
39. Influence of thyroid hormone on androgen metabolism in peripuberal rat Sertoli cells
40. Inhibition of aromatase activity in rat Sertoli cells by thyroid hormone
41. Thyroid hormones effects on mouse oocyte maturation and granulosa cell aromatase activity
42. StAR-A tissue specific acute mediator of steroidogenesis
43. Molecular mechanisms of thyroid hormone-stimulated steroidogenesis in mouse Leydig tumor cells