Regulation of Gadd45γ expression by C/EBP

European Journal of Biochemistry

Volumn 267, Issue 20, 2000, Pages 6180-6187

  Jung, Neoncheol ^a   Yi, Yong Weon ^a   Kim, Daegun ^a   Shong, Minho ^b   Hong, Seung Suh ^a   Lee, Hyun Soo ^a   Bae, Insoo ^a  

^a Samyang Corporation   (South Korea)

^b Chungnam National University   (South Korea)

Author keywords

C EBP; Differentiation; Gadd45; IL 6; Promoter

Indexed keywords

DNA BINDING PROTEIN; INTERLEUKIN 6; TRANSCRIPTION FACTOR; CCAAT ENHANCER BINDING PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; ISOPROTEIN; MESSENGER RNA; PROTEIN; RECOMBINANT PROTEIN; SIGNAL PEPTIDE;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE SEQUENCE; HUMAN; HUMAN CELL; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN FAMILY; TRANSCRIPTION REGULATION; ANIMAL; BIOSYNTHESIS; CELL STRAIN 3T3; DNA DAMAGE; DRUG EFFECT; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; OPEN READING FRAME;

3T3 CELLS; ANIMALS; BASE SEQUENCE; BINDING SITES; CCAAT-ENHANCER-BINDING PROTEINS; CLONING, MOLECULAR; DNA DAMAGE; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PROMOTER REGIONS (GENETICS); PROTEIN ISOFORMS; PROTEINS; RECOMBINANT PROTEINS; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0033623149     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.2000.01692.x     Document Type: Article

References (49)

1. Mammalian genes coordinately regulated by growth arrest signals and DNA-damaging agents
2. Response to adversity: Molecular control of gene activation following genotoxic stress
3. Mammalian genes induced by radiation; activation of genes associated with growth control
4. A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
5. The p53-dependent gamma-ray response of GADD45
6. The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth
7. CR6: A third member in the MyD118 and Gadd45 gene family which functions in negative growth control
8. Interaction of the p53-regulated protein Gadd45 with proliferating cell nuclear antigen
9. Characterisation of the interaction between PCNA and Gadd45
10. Direct interaction of Gadd45 with PCNA and evidence for competitive interaction of Gadd45 and p21Waf1/Cip1 with PCNA
11. The differentiation primary response gene MyD118, related to GADD45, encodes for a nuclear protein which interacts with PCNA and p21WAF1/CIP1
12. A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth
13. Gadd45 is a nuclear cell cycle regulated protein which interacts with p21Cip1
14. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK
15. Does the p53 up-regulated Gadd45 protein have a role in excision repair?
16. Gadd45 is not required for activation of c-Jun N-terminal kinase or p38 during acute stress
17. Stress-induced JNK activation is independent of Gadd45 induction
18. Isolation of interleukin 2-induced immediate-early genes
19. Biological role of the CCAAT/enhancer-binding protein family of transcription factors
20. CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein
21. Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs
22. C/EBPalpha regulation of the growth-arrest-associated gene gadd45
23. CCAAT/enhancer binding proteins are critical components of the transcriptional regulation of hematopoiesis
24. CCAAT/enhancer-binding protein-delta (C/EBP-delta) is induced in growth-arrested mouse mammary epithelial cells
25. CCAAT/enhancer-binding protein delta regulates mammary epithelial cell G0 growth arrest and apoptosis
26. Stat3 as an oncogene
27. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
28. A negative regulatory element and its binding protein in the upstream of enhancer II of hepatitis B virus
29. Phosphorylation of CCAAT-enhancer binding protein by protein kinase C attenuates site-selective DNA binding
30. Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: Differential involvement of c-fos and c-jun protooncogenes
31. 'Western blotting': Electrophoretic transfer of proteins from sodium dodecyl sulfate - Polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A
32. Analysis of the mammalian gadd45 gene and its response to DNA damage
33. IL-6-regulated transcription factors
34. DNA binding specificity of the CCAAT/enhancer-binding protein transcription factor family
35. The ability of C/EBP beta but not C/EBP alpha to synergize with an Sp1 protein is specified by the leucine zipper and activation domain
36. Beta-adrenergic receptor-induced activation of nerve growth factor gene transcription in rat cerebral cortex involves CCAAT/enhancer-binding protein delta
37. Reciprocal regulation of gadd45 by C/EBP alpha and c-Myc
38. A member of the C/EBP family, NF-IL6 beta, forms a heterodimer and transcriptionally synergizes with NF-IL6
39. Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells
40. Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6
41. Calcium-regulated phosphorylation within the leucine zipper of C/EBP beta
42. cAMP stimulates the C/EBP-related transcription factor rNFIL-6 to trans-locate to the nucleus and induce c-fos transcription
43. Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domain
44. Inhibition of cell proliferation by C/EBP alpha occurs in many cell types, does not require the presence of p53 or Rb, and is not affected by large T-antigen
45. Impaired proliferation and tumorigenicity induced by CCAAT/enhancer-binding protein
46. CCAAT/enhancer-binding protein alpha (C/EBP alpha) inhibits cell proliferation through the p21 (WAF-1/CIP-1/SDI-1) protein
47. CCAAT/enhancer binding protein alpha regulates p21 protein and hepatocyte proliferation in newborn mice
48. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6
49. A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells