Design of the Y1-receptor-selective cyclic peptide based on the C-terminal sequence of neuropeptide Y

Journal of Peptide Research

Volumn 56, Issue 6, 2000, Pages 409-415

  Takebayashi, Y ^a   Koga, H ^a   Kurihara, H ^a   Furuya, T ^b   Tanaka, A ^a   Togami, J ^a   Inui, A ^c   Koshiya, K ^d   Murase, K ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b PharmaDesign Inc   (Japan)

^c KOBE UNIVERSITY   (Japan)

^d Yamanouchi USA Inc   (United States)

Author keywords

Binding affinities; Conformational constraints; Cyclic peptide; Neuropeptide Y; Y1 receptor

Indexed keywords

CYCLOPEPTIDE; NEUROPEPTIDE Y; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; YM 42454; PEPTIDE;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONJUGATION; HUMAN; HUMAN CELL; MOLECULAR MODEL; PEPTIDE ANALYSIS; PRIORITY JOURNAL; RECEPTOR BINDING; STRUCTURE ANALYSIS; ANIMAL; BRAIN; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDE SYNTHESIS; PROTEIN BINDING; PROTEIN CONFORMATION; SWINE;

ANIMALS; BRAIN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; NEUROPEPTIDE Y; PEPTIDE BIOSYNTHESIS; PEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SWINE; TUMOR CELLS, CULTURED;

EID: 0033622496     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2000.00788.x     Document Type: Article

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