Effect of phospholipase A2 inhibitors on the release of arachidonic acid and cell viability in cold-stored hepatocytes

Cryobiology

Volumn 40, Issue 1, 2000, Pages 27-35

  Kim, Jae Sung ^a   Southard, James H ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Hepatocytes; Phospholipase A2; Preservation injury

Indexed keywords

ARACHIDONIC ACID; ARISTOLOCHIC ACID; CHLORPROMAZINE; LACTATE DEHYDROGENASE; MEPACRINE; PHOSPHOLIPASE A2 INHIBITOR; TRIFLUOPERAZINE; UNIVERSITY OF WISCONSIN SOLUTION; ENZYME INHIBITOR; PHOSPHOLIPASE A;

ANIMAL CELL; ARTICLE; CELL DEATH; CELL VIABILITY; CRYOPRESERVATION; ENZYME ACTIVITY; ENZYME RELEASE; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; ANIMAL; CELL SURVIVAL; DRUG ANTAGONISM; LIVER; METABOLISM; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; ARACHIDONIC ACID; CELL SURVIVAL; CRYOPRESERVATION; ENZYME INHIBITORS; LIVER; MALE; PHOSPHOLIPASES A; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0033621711     PISSN: 00112240     EISSN: None     Source Type: Journal    
DOI: 10.1006/cryo.1999.2217     Document Type: Article

References (23)

1. Anaise D., Ishimaru M., Madariaga J., Irisawa A., Lane B., Zeidan B., Sonoda K., Shabtai M., Waltzer W. C., Rapaport F. T. Protective effects of trifluoperazine on the microcirculation of cold-stored livers. Transplantation. 50:1990;933-939.
2. Ar'Rajab A., Ahren B., Nilsson A. Temperature-dependent phospholipid degradation in the rat liver during preservation for transplantation. Transplantation. 57:1994;1153-1160.
3. Bernardini D., Benkoel L., Botta-Fridlund D., Le Treut Y. P., Lafont H., Gauthier A., Chanussot F., Chamlian A. Time-related changes of cold-stored rat liver in University of Wisconsin solution: Effect of ursodeoxycholate. Cell. Mol. Biol. 42:1996;487-500.
4. Bonventre J., Nemenoff R. Renal tubular arachidonic acid metabolism. Kidney Int. 39:1991;438-449.
5. Chien K. R., Abrams J., Serroni A., Martin J. T., Farber J. L. Accelerated phospholipid degradation and associated membrane dysfunction in irreversible, ischemic liver cell injury. J. Biol. Chem. 253:1978;4809-4817.
6. Claesson K., Lindell S., Southard J. H., Belzer F. O. Chlorpromazine, quinacrine, and verapamil as donor pretreatment in liver preservation, tested in the isolated perfused rat liver. Cryobiology. 28:1991;422-427.
7. Clavien P.-A., Harvey P. R. C., Strasberg S. M. Preservation and reperfusion injuries in liver allografts. Transplantation. 53:1992;957-978.
8. Das D. K., Engelman R. M., Rousou J. A., Breyer R. H., Otani H., Lemeshow S. Role of membrane phospholipids in myocardial injury induced by ischemia and reperfusion. Am. J. Physiol. 251:1986;H71-H79.
9. Folch J., Lees M., Stanley G. H. S. A simple method for the isolation and purification of total lipids from animal tissues. J. Biol. Chem. 226:1957;497-509.
10. Hamamoto I., Nemoto E. M., Evans R. W., Mischinger H.-J., Fujita S., Murase N., Todo S. Rat liver lipids during ex vivo warm and cold ischemia and reperfusion. J. Surg. Res. 55:1993;382-389.
11. 2 contributes to loss of plasma membrane integrity during chemical hypoxia in rat hepatocytes. Biochem. Biophys. Res. Commun. 174:1991;654-659.
12. Hazel J. R., Hagar A. F., Pruitt N. L. The temperature dependence of phospholipid deacylation/reacylation in isolated hepatocytes of thermally acclimated rainbow trout (Salmo gairdneri). Biochim. Biophys. Acta. 918:1987;149-158.
13. Hillyard L. A., Entenman C. Effect of low temperature on metabolism of rat liver slices and epididymal fat pads. Am. J. Physiol. 224:1973;148-153.
14. Kim J.-S., Southard J. H. Alteration in cellular calcium and mitochondrial functions in the rat liver during cold preservation. Transplantation. 65:1998;369-375.
15. Kim J-S., Southard J. H. Phospholipid metabolism of hypothermically stored rat hepatocytes. Hepatology. 30:1999;1232-1240.
16. Liu X., Prasad M. R., Engelman R. M., Jones R. M., Das D. K. Role of iron on membrane phospholipid breakdown in ischemic-reperfused rat heart. Am. J. Physiol. 259:1990;H1101-H1107.
17. MacDonald J. I. S., Sprecher H. Phospholipid fatty acid remodeling in mammalian cells. Biochim. Biophys. Acta. 1084:1991;105-121.
18. Marsh D. C., Hjelmhaug J. A., Vreugdenhil P. K., Belzer F. O., Southard J. H. Glycine prevention of cold ischemic injury in isolated hepatocytes. Cryobiology. 28:1991;105-109.
19. McAnulty J. F., Vreugdenhil P. K., Southard J. H. Improved survival of kidneys preserved for seven days with a phospholipase inhibitor. Transplant. Proc. 23:1991;691-692.
20. 2+ and the stimulation of a nonlysosomal proteolytic system. J. Biol. Chem. 261:1986;14628-14635.
21. 2+ homeostasis in cultured rat hepatocytes intoxicated with cyanide. Am. J. Physiol. 263:1992;C684-C690.
22. Tokunaga Y., Wicomb W. N., Concepcion W., Nakazato P., Collins G. M., Esquivel C. O. Successful 20-hour rat liver preservation with chlorpromazine in sodium lactobionate sucrose solution. Surgery. 110:1991;80-86.
23. Weltzien H. U. Cytolytic and membrane-perturbing properties of lysophosphatidylcholine. Biochim. Biophys. Acta. 559:1979;259-287.