Legg-Calvé-Perthes disease, protein C deficiency, and β-thalassemia major: Report of two cases

Journal of Pediatric Orthopaedics

Volumn 20, Issue 1, 2000, Pages 129-131

  Levin, Carina ^a   Zalman, Lucia ^a   Shalev, Stavit ^a   Mader, Rivka ^a   Koren, Ariel ^a,b  

^a HAEMEK MEDICAL CENTER   (Israel)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Aseptic necrosis; Legg Calv Perthes disease; Protein C deficiency Thrombophilia; Thalassemia

Indexed keywords

PROTEIN C;

ADOLESCENT; ARTICLE; AVASCULAR NECROSIS; CASE REPORT; DISEASE ASSOCIATION; FEMUR HEAD NECROSIS; HUMAN; MALE; PERTHES DISEASE; PRIORITY JOURNAL; PROTEIN C DEFICIENCY; SCHOOL CHILD; THALASSEMIA MAJOR; THROMBOPHILIA; BETA THALASSEMIA; CHILD; REVIEW;

ADOLESCENT; BETA-THALASSEMIA; CHILD; HUMANS; LEGG-PERTHES DISEASE; MALE; PROTEIN C DEFICIENCY;

EID: 0033621677     PISSN: 02716798     EISSN: None     Source Type: Journal    
DOI: 10.1097/01241398-200001000-00025     Document Type: Article

References (9)

1. Borgna Pignatti C, Carnelli V, et al. Thromboembolic events in beta thalassemia major: an Italian multicenter study. Acta Haematol 1998;99:76-9.
2. Cheras PA, Whitaker AN, Blackwell EA, Sinton TJ, Chapman MD, Peacock KA. Hypercoagulability and hypofibrinolysis in primary osteoarthritis. Clin Orthop 1997;334:57-67.
3. Eldor A, Lellouche F, Goldfarb A, Rachmilewitz EA, Maclouf J. In vivo platelet activation in β-thalassemia major reflected by increased platelet-thromboxane urinary metabolites. Blood 1991;77: 1749-53.
4. Glueck CJ, Crawford A, Roy D, Freiberg R, Glueck H, Stroop D. Association of antithrombotic factor deficiencies and hypofibrinolysis with Legg-Perthes disease. J Bone Joint Surg Am 1996;78: 3-13.
5. Jones JP. Fat embolism and osteonecrosis. Orthop Clin North Am 1985;16:595-633.
6. Koop S, Quanbeck D. Three common causes of childhood hip pain. Pediatr Clin North Am 1996;43:1053-66.
7. Leonardi S, Arcidiacono G, Colianni R, Di Gregorio L, Musumeci S. Protein S, protein C, and antithrombin III in thrombotic disease: their role in β-thalassemia major. Ann N Y Acad Sci 1990;612: 549-52.
8. Musumeci S, Leonardi S, Di Dio R, Fisher A, Di Costa G. Protein C and antithrombin III in polytransfused thalassemic patients. Acta Haematol 1987;77:30-3.
9. O'Driscoll A, Mackie IJ, Porter JB, Machin SJ. Low plasma heparin cofactor II levels in thalassaemia syndromes are corrected by chronic blood transfusion. Br J Haematol 1995;90:65-70.