Cloning of a cysteine proteinase gene from Acanthamoeba culbertsoni

Molecules and Cells

Volumn 9, Issue 5, 1999, Pages 491-496

  Yun, Ho Cheol ^a   Kim, Kwang Yong ^a   Park, Seong Yeol ^a   Park, Seung Kyu ^a   Park, Hyun ^a   Hwang, Ui Wook ^b   Hong, Kyeong Man ^a   Ryu, Jae Sook ^c   Min, Duk Young ^c  

^a Wonkwang University   (South Korea)

^b Yonsei University   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

Acanthamoeba culbertsoni; Cathepsin L like Structure; Cysteine Proteinase Gene; Phylogenetic Relationships

Indexed keywords

CATHEPSIN; CATHEPSIN L; COMPLEMENTARY DNA; CYSTEINE PROTEINASE; HELMINTH PROTEIN; PROTEINASE; PROTOZOAL PROTEIN; VEGETABLE PROTEIN;

ACANTHAMOEBA; AMINO ACID SEQUENCE; ANIMAL; ARTICLE; COMPARATIVE STUDY; ENZYMOLOGY; EVOLUTION; GENE; GENETICS; HUMAN; MOLECULAR CLONING; MOLECULAR GENETICS; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PHYLOGENY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SPECIES DIFFERENCE;

ACANTHAMOEBA; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; CATHEPSINS; CLONING, MOLECULAR; CYSTEINE ENDOPEPTIDASES; DNA, COMPLEMENTARY; ENDOPEPTIDASES; EVOLUTION; GENES, PROTOZOAN; HELMINTH PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PHYLOGENY; PLANT PROTEINS; PROTOZOAN PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY;

EID: 0033621213     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Chappell, C. L. and Dresden, M. H. (1987) Purification of cysteine proteinases from adult Schistosoma mansoni. Arch. Biochem. Biophys. 256, 560-568.
2. Chomczynski, P. and Sacchi, N. (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenolchloroform extraction. Anal. Biochem. 162, 156-159.
3. Fowler, M. and Carter, R. F. (1965) Acute pyogenic meningitis probably due to Acanthamoeba species: a preliminary report. Brit. Med. J. 2, 740-742.
4. Gillmor, S. A. and Cohen, F. E. (1993) New strategies for pharmaceutical design. Receptor 3, 155-163
5. Gubler, U. and Hoffman, B. J. (1983) A simple and very efficient method for generating cDNA libraries. Gene 25, 263-269.
6. Hadas, E. and Mazur, T. (1993) Proteolytic enzymes of pathogenic and non-pathogenic strains of Acanthamoeba spp. Trop. Med. Parasitol. 44, 197-200.
7. von Heijne (1983) Patterns of amino acids near signal-sequence cleavage site. Eur. J. Biochem. 133, 17-21.
8. Heussler, V. T., Eichhorn, M., Reeves, R., Magnuson, N. S., Williams, R. O., and Dobbelaere, D. A. (1992) Constitutive IL-2 mRNA expression in lymphocytes, infected with the intracellular parasite Theileria parva. J. Immunol. 149, 562-567.
9. Heussler, V. T. and Dobbelaere, D. A. E. (1994) Cloning of a protease gene family of Fasciola hepatica by the polymerase chain reaction. Mol. Biochem. Parasitol. 64, 11-23.
10. Joseph, L. J., Chang, L. C., Stamenkovich, D., and Sukhatme, V. P. (1988) Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts. J. Clin. Invest. 81, 1621-1629.
11. Karrer, K. M., Peiffer, S. L., and Ditomas, M. E. (1993) Two distinct gene subfamilies within the family of cysteine protease genes. Proc. Natl. Acad. Sci. USA 90, 3063-3067.
12. Kim, T. U. (1990) Biochemical study on the cytotoxic substance of free living amoeba. Dissertation for Ph.D., Yonsei University, Korea.
13. Kuntz, I. D. (1992) Structure-based strategies for drug design and discovery. Science 257, 1078-1082.
14. Mckerrow, J. H., Cohen, F. E., Craik, C. S., and Sakanari, J. A. (1992) New approaches to isolation, expression and molecular modeling of proteases; in Medicinal Chemistry for the 21st Century, Wermuth, C. G., Koga, N., Konig, H., and Metcalf, B. W. (eds.), pp. 107-118, Blackwell Science, Oxford.
15. Mckerrow, J. H., Sun, E., Rosenthal, P. J., and Bouvier, J. (1993) The proteases and pathogenicity of parasitic protozoa. Annual Rev. Microbiol. 47, 821-853.
16. North, M. J., Mottram, J. C., and Coombs, G. H. (1990) Cysteine proteinases of parasitic protozoa. Parasitol. Today 6, 270-275.
17. Park, H., Ko, M. Y., Paik, M. K., Soh, C. T., Seo, J. H., and Im, K. I. (1995) Cytotoxicity of a cysteine proteinase of adult Clonorchis sinensis. Korean J. Parasitol. 33, 211-218.
18. Rege, A. A., Herrera, P. R., Lopez, M., and Dresden, M. H. (1989) Isolation and characterization of a cysteins proteinase from Fasciola hepatica adult worms. Mol. Biochem. Parasitol. 35, 89-96.
19. Robertson, C. D., North, M. J., Lockwood, B. C., and Coombs, G. H. (1990) Analysis of the proteinases of Trypanosoma brucei. J. Gen. Microbiol. 136(Pt5), 921-925.
20. Smith, A. M., Dalton, J. P., Clough, K. A., Kilbane, C. L., Harrop, S. A., Hole, N., and Brindley, P. J. (1994) Adult Schistosoma mansoni express cathepsin L proteinase activity. Mol. Biochem. Parasitol. 67, 11-19.
21. Sun. E., Cohen, F. E. ( 1993) Computer-assisted drug discovery -A review. Gene 137, 124-127.
22. Taylor, M. A. J., Baker, K. C., Briggs, G. S., Connerton, I. F., Cummings, N. J., Pratt. K. A., Revell, D. F., Freedman, R. B., and Goodenough, P. W. (1995) Recombinant pro-regions from papain and papaya proteinase IV are selective high affinity inhibitors of the mature papaya enzymes. Protein Engineering 8, 59-62.
23. Yamamoto, M., Yamakami, K., and Hamajima, F. (1994) Cloning of a cDNA encoding a neutral thiol protease from Paragonimus westermani metacercariae. Mol. Biochem. Parasitol. 64, 345-348.