Efficient synthesis of enantiomerically pure thioester precursors of [11C]McN-5652 from racemic McN-5652

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 42, Issue 13, 1999, Pages 1301-1312

  Zessin, J ^a   Gucker, P ^b   Ametamey, S M ^b   Steinbach, J ^a   Brust, P ^a   Vollenweider, F X ^c   Johannsen, B ^a   Schubiger, P A ^b  

^a INSTITUTE OF ION BEAM PHYSICS AND MATERIALS RESEARCH   (Germany)

^b PAUL SCHERRER INSTITUTE   (Switzerland)

^c Psychatric University Hospital   (Switzerland)

Author keywords

PET; Serotonin uptake sites; 11C labelling

Indexed keywords

AMIDES; CHEMICAL REACTIONS; ENANTIOMERS; SODIUM COMPOUNDS;

ACETYL CHLORIDE; DEMETHYLATION; EFFICIENT SYNTHESIS; ENANTIOMERIC PURITY; LABELINGS; LOWS-TEMPERATURES; SEROTONIN UPTAKE SITE; SYNTHETIC METHODS; THIOESTERS; [11C]-LABELING;

CHLORINE COMPOUNDS;

1,2,3,5,6,10B HEXAHYDRO 6 (4 METHYLTHIOPHENYL)PYRROLO[2,1 A]ISOQUINOLINE; ACETIC ACID DERIVATIVE; AMIDE; CARBON 11; CHLORIDE; SODIUM; THIOESTER; THIOL;

ARTICLE; CRYSTALLIZATION; DEMETHYLATION; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOMER; PRECURSOR; PURIFICATION; RACEMIC MIXTURE; RADIOACTIVITY; RADIOCHEMISTRY; TEMPERATURE;

EOS;

EID: 0033620002     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(19991230)42:13<1301::AID-JLCR298>3.0.CO;2-2     Document Type: Article

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