Activation of the thymidine kinase promoter by herpes simplex virus type 1 immediate early proteins

Molecules and Cells

Volumn 9, Issue 3, 1999, Pages 277-280

  Kwun, Hyun Jin ^a   Yim, Sung Wan ^a   Lee, Dong Hee ^b   Jang, Kyung Lib ^a  

^a Pusan National University   (South Korea)

^b Dong Eui University   (South Korea)

Author keywords

CTF; HSV; Immediate early proteins; Thymidine Kinase

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; CTF 1 TRANSCRIPTION FACTOR; CTF-1 TRANSCRIPTION FACTOR; DNA BINDING PROTEIN; IMMEDIATE EARLY PROTEIN; NUCLEAR FACTOR I; THYMIDINE KINASE; TRANSCRIPTION FACTOR; VIRUS DNA;

ANIMAL; ARTICLE; BINDING SITE; CELL LINE; ENZYMOLOGY; GENETICS; HAMSTER; HERPES SIMPLEX VIRUS 1; METABOLISM; MUTATION; NUCLEOTIDE SEQUENCE; PLASMID; PROMOTER REGION; VIRUS GENE;

ANIMALS; BASE SEQUENCE; BINDING SITES; CCAAT-ENHANCER-BINDING PROTEINS; CELL LINE; CRICETINAE; DNA, VIRAL; DNA-BINDING PROTEINS; GENES, VIRAL; HERPESVIRUS 1, HUMAN; IMMEDIATE-EARLY PROTEINS; MUTATION; NFI TRANSCRIPTION FACTORS; PLASMIDS; PROMOTER REGIONS (GENETICS); THYMIDINE KINASE; TRANSCRIPTION FACTORS;

EID: 0033617765     PISSN: 10168478     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Cai, W., Astor, T. L., Liptak, L. M., Cho, C., Coen, D. M., and Schaffer, P. A. (1993) The herpes simplex virus type 1 regulatory protein ICP0 enhances virus replication during acute infection and reactivation from latency. J. Virol. 67, 7505-7512.
2. Cai, W. and Schaffer, P. A. (1989) Herpes simplex virus type 1 ICP0 plays a critical role in the de novo synthesis of infectious virus following transfection of viral DNA. J. Virol. 63, 4579-4589.
3. Cai, W. and Schaffer, P. A. (1992) Herpes simplex virus type 1 ICP0 regulates expression of immediate-early, early, and late genes in productively infected cells. J. Virol. 66, 2904-2915.
4. Chen, J. and Silverstein, S. (1992) Herpes simplex viruses with mutations in the gene encoding ICP0 are defective in gene expression. J. Virol. 66, 2916-2927.
5. Clements, J. B., Watson, R. J., and Wilkie, N. M. (1977) Temporal regulation of herpes simplex virus type 1 transcription: location of transcripts on the viral genome. Cell 12, 275-285.
6. DeLuca, N. A., McCarthy, A. M., and Schaffer, P. A. (1985) Isolation and characterization of deletion mutants of herpes simplex virus type 1 in the gene encoding immediate-early regulatory protein ICP4. J. Virol. 56, 558-570.
7. DeLuca, N. A. and Schaffer P. A. (1988) Physical and functional domains of the herpes simplex virus transcriptional regulatory protein ICP4. J. Virol. 62, 732-743.
8. Everett, R. D. (1986) The products of herpes simplex virus type 1 (HSV-1) immediate early genes 1, 2 and 3 can activate HSV-1 gene expression in trans. J. Gen. Virol. 67, 2507-2513.
9. Everett, R. D. (1988) Analysis of functional domains of herpes simplex virus type 1 immediate early polypeptide Vmw110. J. Mol. Biol. 202, 87-96.
10. Everett, R. D. (1989) Construction and characterization of herpes simplex type 1 mutants with defined lesions in immediate-early gene 1. J. Gen. Virol. 70, 1185-1202.
11. Gorman, C. M. (1985) High efficiency gene transfer into mammalian cells; in DNA Cloning, a Practical Approach, Glover, D. M. (ed.), pp. 143-190, IRL Press, Oxford.
12. Honess, R. W. and Roizman, B. (1974) Regulation of herpesvirus macro-molecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins. J. Virol. 14, 8-19.
13. Honess, R. W. and Roizman, B. (1975) Regulation of herpesvirus macro-molecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides. Proc. Natl. Acad. Sci. USA 72, 1276-1280.
14. Imbalzano, A. N., Coen, D. M., and Deluca, N. A. (1991) Herpes simplex virus transactivator ICP4 operationally substitutes for the cellular transcription factor Sp1 for efficient expression of the viral thymidine kinase gene. J. Virol. 65, 565-574.
15. Jang, K. L. (1995) The herpes simplex virus immediate-early protein ICP27 activates the transcription of Alu repeats by polymerase III. Mol. Cells 5, 419-424.
16. Jones, K. A., Yamamoto, K. R., and Tjian, R. (1985) Two distinct transcription factors bind to the HSV thymidine kinase promoter in vitro. Cell 42, 559-572.
17. Marvromara-Nazos, P., Ackermann, M., and Roizman, B. (1986) Construction and properties of a viable herpes simplex virus 1 recombinant lacking the coding sequences of the α47 gene. J. Virol. 60, 807-812.
18. McCarthy, A. M., McMahan, L., and Schaffer, P. A. (1989) Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient. J. Virol. 63, 18-27.
19. McKnight, S. L. and Gavis, E. R. (1980) Expression of the herpes thymidine kinase gene in Xenopus laevis oocytes: an assay for the study of deletion mutants constructed in vitro. Nucleic Acids Res. 8, 5931-5948.
20. McKnight, S. L., Gavis, E. R., Kingsbury, R., and Axel, R. (1981) Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: identification of an upstream control region. Cell 25, 385-398.
21. McKnight, S. L. and Kingsbury, R. (1982) Transcriptional control signals of a eukaryotic protein-coding gene. Science 217, 316-324.
22. Miksicek, R., Heber, A., Schmid, W., Danesch, U., Posseckert, G., Beato, M., and Schutz, G. (1986) Glucocorticoid responsiveness of the transcriptional enhancer of moloney murine sarcoma virus. Cell 46, 283-290.
23. O'Hare, P. and Hayward, G. S. (1987) Comparisor of upstream sequence requirements for positive and negative regulation of a herpes simplex virus immediate-early gene by three virus-encoded trans-acting factors. J. Virol. 61, 190-199.
24. Sacks, W. R. and Schaffer, P. A. (1987) Deletion mutants in the gene encoding the herpes simplex virus type 1 immediate-early protein ICP0 exhibit impaired growth in cell culture. J. Virol. 61, 829-839.
25. Sekulovich, R. E., Leary, K., and Sandri-Goldin, R. M. (1988) Herpes simplex virus type 1 alpha protein ICP27 can act as a trans-repressor or a trans-activator in combination with ICP4 and ICP0. J. Virol. 62, 4510-4522.
26. Stow, N. D. and Stow, E. C. (1986) Isolation and characterization of a herpes simplex virus type 1 mutant containing a deletion within the gene encoding the immediate early polypeptide Vmw110. J. Gen. Virol. 67, 2571-2585.
27. Su, L. and Knipe, D. M. (1989) Herpes simplex virus alpha protein ICP27 can inhibit or augment viral gene transactivation. Virology 170, 496-504.