Mapping the active site in vasoactive intestinal peptide to a core of four amino acids: Neuroprotective drug design

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 7, 1999, Pages 4143-4148

  Gozes, I ^a   Perl, O ^a   Giladi, E ^a   Davidson, A ^a   Ashur Fabian, O ^a   Rubinraut, S ^b   Fridkin, M ^b  

^a TEL AVIV UNIVERSITY   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; NEUROPEPTIDE; STEARIC ACID; VASOACTIVE INTESTINAL POLYPEPTIDE;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL MODEL; ARTICLE; BINDING SITE; COGNITIVE DEFECT; CONTROLLED STUDY; DEGENERATIVE DISEASE; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG POTENCY; DRUG STABILITY; ENZYME ACTIVITY; INTRANASAL DRUG ADMINISTRATION; MOLECULAR DYNAMICS; NERVE CELL; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANIMALS, NEWBORN; APOLIPOPROTEINS E; ASTROCYTES; BINDING SITES; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; DRUG DESIGN; METHIONINE; MOLECULAR SEQUENCE DATA; NEUROGLIA; NEURONS; NEUROPROTECTIVE AGENTS; NORLEUCINE; OLIGOPEPTIDES; RATS; VASOACTIVE INTESTINAL PEPTIDE;

ANIMALIA;

EID: 0033616805     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.7.4143     Document Type: Article

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