A novel C-type lectin secreted by a tissue-dwelling parasitic nematode

Current Biology

Volumn 9, Issue 15, 1999, Pages 825-828

  Loukas, Alex ^a   Mullin, Nicholas P ^a   Tetteh, Kevin K A ^a   Moens, Luc ^b   Maizels, Rick M ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

LECTIN;

CANIS; MAMMALIA; NEMATODA; TOXOCARA CANIS;

EID: 0033615071     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(99)80366-2     Document Type: Article

References (20)

1. Page AP, Hamilton AJ, Maizels RM: Toxocara canis: Monoclonal antibodies to carbohydrate epitopes of secreted (TES) antigens localize to different secretion-related structures in infective larvae. Exp Parasitol 1992, 75:56-71.
2. Maizels RM, Kennedy MW, Meghji M, Robertson BD, Smith HV: Shared carbohydrate epitopes on distinct surface and secreted antigens of the parasitic nematode Toxocara canis. J Immunol 1987, 139:207-214.
3. Tetteh KKA, Loukas A, Tripp C, Maizels RM: Identification of abundantly-expressed novel and conserved genes from the infective larval stage of Toxocara canis by an expressed-sequence tag strategy. Infect Immun 1999, in press.
4. Meghji M, Maizels RM: Biochemical properties of larval excretory-secretory (ES) glycoproteins of the parasitic nematode Toxocara canis. Mol Biochem Parasitol 1986, 18:155-170.
5. Page AP, Maizels RM: Biosynthesis and glycosylation of serine/threonine-rich secreted proteins from Toxocara canis larvae. Parasitology 1992, 105:297-308.
6. Weis WI, Drickamer K, Hendrickson WA: Structure of a C-type mannose-binding protein complexed with an oligosaccharide. Nature 1992, 360:127-134.
7. Drickamer K: Engineering galactose-binding activity into a C-type mannose-binding protein. Nature 1992, 360:183-186.
8. Iobst ST, Drickamer K: Binding of sugar ligands to Ca(2+)-dependent animal lectins. II. Generation of high-affinity galactose binding by site-directed mutagenesis. J Biol Chem 1994, 269:15512-15519.
9. Kolatkar AR, Weis WI: Structural basis of galactose recognition by C-type animal lectins. J Biol Chem 1996, 271:6679-6685.
10. Weis WI, Taylor ME, Drickamer K: The C-type lectin superfamily in the immune system. Immunol Rev 1998, 163:19-34.
11. Wilson R, Chen C, Ratcliffe NA: Innate immunity in insects: The role of multiple, endogenous serum lectins in the recognition of foreign invaders in the cockroach, Blaberus discoidalis. J Immunol 1999, 162:1590-1596.
12. The C.elegans Genome Sequence Consortium: Genome sequence of Caenorhabditis elegans: A platform for investigating biology. Science 1998, 282:2012-2018.
13. Khoo K-H, Maizels RM, Page AP, Taylor GW, Rendell N, Dell A: Characterisation of nematode glycoproteins: The major O-glycans of Toxocara excretory secretory antigens are methylated trisaccharides. Glycobiology 1991, 1:163-171.
14. Gems DH, Maizels RM: An abundantly expressed mucin-like protein from Toxocara canis infective larvae: The precursor of the larval surface coat glycoproteins. Proc Natl Acad Sci USA 1996, 93:1665-1670.
15. Maizels RM, Bundy DAP, Selkirk ME, Smith DF, Anderson RM: Immunological modulation and evasion by helminth parasites in human populations. Nature 1993, 365:797-805.
16. Page AP, Richards DT, Lewis JW, Omar HM, Maizels RM: Comparison of isolates and species of Toxocara and Toxascaris by biosynthetic labelling of somatic and ES proteins from infective larvae. Parasitology 1991, 103:451-464.
17. Coligan JE, Kruisbeek AM, Margulies DH, Shevach EM, Strober W: Current Protocols in Immunology. New York: Greene Publishing Associates and Wiley-Interscience; 1997.
18. Burrows L, Lobst ST, Drickamer K: Selective binding of N-acetylglucosamine to the chicken hepatic lectin. Biochem J 1997, 324:673-680.
19. Sali A, Blundell TL: Comparative protein modelling by satisfaction of spatial restraints. J Mol Biol 1993, 234:779-815.
20. Kraulis PJ: MOLSCRIPT: A program to produce both detailed and schematic plots of protein structures. J Appl Crystallogr 1991, 24:946-950.