Structure-activity relationships in 1,4-benzodioxan-related compounds. 6. Role of the dioxane unit on selectivity for α1-adrenoreceptor subtypes

Journal of Medicinal Chemistry

Volumn 42, Issue 15, 1999, Pages 2961-2968

  Quaglia, Wilma ^a   Pigini, Maria ^a   Piergentili, Alessandro ^a   Giannella, Mario ^a   Marucci, Gabriella ^a   Poggesi, Elena ^b   Leonardi, Amedeo ^b   Melchiorre, Carlo ^c  

^a UNIVERSITY OF CAMERINO   (Italy)

^b Recordati SpA   (Italy)

^c UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 BENZODIOXAN DERIVATIVE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 2 [[2 (2,6 DIMETHOXYPHENOXY)ETHYL]AMINOMETHYL] 1,4 BENZODIOXAN; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 1A ADRENERGIC RECEPTOR; ALPHA 1D ADRENERGIC RECEPTOR; RECEPTOR SUBTYPE; SEROTONIN 1A RECEPTOR;

ALPHA ADRENERGIC RECEPTOR BLOCKING; ANIMAL TISSUE; AORTA; ARTICLE; CHO CELL; CONTROLLED STUDY; CORPUS STRIATUM; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SPECIFICITY; GUINEA PIG; HELA CELL; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; SPLEEN; STRUCTURE ACTIVITY RELATION; VAS DEFERENS;

EID: 0033615029     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9910324     Document Type: Article

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