Simple and rapid visual sensing of saccharides

Organic Letters

Volumn 1, Issue 2, 1999, Pages 331-334

  Davis, Claude J ^a   Lewis, Patrick T ^a   McCarroll, Matthew E ^a   Read, Mark W ^a   Cueto, Rafael ^a   Strongin, Robert M ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZHYDRYL DERIVATIVE; BORON DERIVATIVE; CARBOHYDRATE;

ARTICLE; COLORIMETRY; SPECTROFLUOROMETRY; SYNTHESIS;

BENZHYDRYL COMPOUNDS; BORON COMPOUNDS; CARBOHYDRATES; COLORIMETRY; SPECTROMETRY, FLUORESCENCE;

EID: 0033614854     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol990105a     Document Type: Article

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13. 4 produces only a very faint yellow tint which is also observed via heating in the presence of 3 equiv added glucose, fructose, and sucrose.
14. 2. These experiments demonstrate that the macrocyclic structure is a prerequisite for attaining the dramatic color changes observed. We are investigating the possibility of the role of sugar (beyond simple boronate ester formation and hydrogen bonding; e.g., furfural or other sugar-derived aldehyde condensation) reactions with 1 or oxidized, potentially ring-opened 1. In addition, comparative studies of the coloration process employing 1 and simple aliphatic and aromatic diols vs other hydoxy compounds, reducing vs nonreducing sugars, and ketoses vs aldoses in buffered solutions are in progress.
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